Vinpocetine is a semisynthetic derivative of the alkaloid vincamine, an extract from the periwinkle plant. Vinpocetine is reported to have cerebral blood-flow enhancing and neuroprotective effects, and is usedas a drug in Eastern Europe for the treatment of cerebrovascular disorders and age-related memoryimpairment.
S Sample IR spectrum matches reference standard IR spectrum
White or slightly yellow, crystalline powder
Specific Rotation, C=1 [a]D20
+127 ~ +134
Practically insoluble in water
Soluble in methylene chloride
Slightly soluble in anhydrous ethanol
Impurity A: 0.6% Max.
Impurity B: 0.5% Max.
Impurity C: 0.3% Max.
Impurity D: 0.5% Max.
Unspecified Impurity: 0.1% Max.
Loss on Dried
Assay (On dried basis)
98.5%-101.5% by HPLC
1. Vinpocetine is applicable to the sequelae of cerebral infarction, cerebral hemorrhage sequelae, cerebral arteriosclerosis etc.. 2. Vinpocetine is cerebral vasodilator, inhibit phosphodiesterase activity, increased vascular smooth muscle relaxation effect of messenger c-GMP, selectively increase cerebral blood flow, in addition can inhibit platelet aggregation, reduce blood viscosity, enhance the red cell deformation force, improve liquidity and microcirculation, promote brain tissue glucose uptake, increased brain oxygen consumption, improve cerebral metabolism.
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