Mebendazole is thought to kill worms byselectively inhibiting the synthesis of microtubules, impairing the parasite'sability to utilise glucose.
drug interaction:cimetidine raisesserum mebendazole levels, increasing its effectiveness.(toxic epidermalnecrolysis) when mebendazole is combined with high doses of metronidazole.
Mebendazole is thought to work by selectively inhibiting the synthesis of microtubules in parasitic worms, and by destroying extant cytoplasmic microtubes in their intestinal cells: thereby blocking the uptake of glucose and other nutrients, resulting in the gradual immobilization and eventual death of the helminths. The drug is a highly effective broad spectrum antihelminitic indicated for the treatment of nematode infestations, including round worm, whip worm, thread worm, and hook worm. It is poorly absorbed and has no systemic effects.
A white or almost white powder
Almost white powder
Practically insoluble in water,in alcohol and in methylene chloride,It shows polymorphism
Comform to the spectrum obtained from Mebendazole RS.
Impurity G not more than 0.5%
Any other individual impurity not more than 0.25%
Total impurities not more than 1.0%
Loss on drying
Not more than 0.5%
Residue on ignition
Not more than 0.1%
Partical size distribution
Particals smaller than 20um should be no less than 90%
It contains not less than 99.0% and not more than 101.0% of C16H13N3O3 calculated on the dried basis
Packaging & Shipping
Qingdao Sigma Chemical Co., Ltd.is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
The aim of Qingdao Sigma Chemical Co., Ltdis a quality policy that"Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
Qingdao Sigma Chemical Co., Ltd has become the "Top 500 Chinese manufacturing companies",
"Top 20 of global chemical sales".Qingdao Sigma Chemical Co., Ltdhas 21 subsidiaries and holding companies.
Q1: Are you a manufacturer? Answer: Yes, we are factory founded on 2002.
Q2: How to contact with us? Click the Alibaba"Contact Supplier" And then send us message the product you interest in, you will get reply within 24 hours.
Q3:Which kind of payment terms do you accept? For small order,you can pay by T/T,Western Union or Paypal,nomal order by T/T to our company account
Q4:Can you give me a discount price? Surely,It depend on your qty
Q5:How can i get a sample? free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
Q6: How to confirm the Product Quality before placing orders? A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q7:How do you treat quality complaint? A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.