Sotalol hydrochloride is a compound categorized with class III antiarrhythmic activity with a mechanism of action that prolongs theaction potential and refraction of cardiac tissue through non-selective yet potent β-adronergic blocking activity. Sotalol hydrochloride is also considered a non-selective β blocker and a potassium channel blocker with an IC50 of 43 µM.
Solution clarity and color
solution should be clear and colorless
Total other impurity
Loss on drying
Residue on ignition
Assay(on dried basis)
Arrhythmia, especially ventricular tachyarrhythmias and life-threatening, symptomatic nonsustained ventricular tachyarrhythmias and symptomatic ventricular premature beat, cardiac surgery after paroxysmal atrial tachycardia, paroxysmal atrial fibrillation, atrioventricular nodal reentrant tachycardia, paroxysmal atrioventricular reentrant bypass tachycardia and supraventricular tachycardia prevention. To maintain normal sinus rhythm after cardioversion of atrial fibrillation or flutter. Excessive catecholamine in circulating blood and arrhythmia caused by an increase in sensitivity to catecholamine. The incidence of angina and the degree of attack were reduced, and exercise tolerance was increased. 5-14 days after the onset of acute myocardial infarction in given can significantly reduce the incidence of re infarction. Hypertension.
Packaging & Shipping
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