BP Grade domperidone powder 99% Domperidone with best price CAS 57808-66-9

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BP Grade domperidone powder 99% Domperidone with best price CAS 57808-66-9

BP Grade domperidone powder 99% Domperidone with best price CAS 57808-66-9

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    MOQ 1 Kilogram
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From $ 84.2084.10  / Kilogram
$ 84.20
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If over 500pcs, mass production will start until pre-production sample has been approved.

Est. 7 days production

Functions

V2-Product Profile

Product Name:
Domperidone
CAS NO:
57808-66-9
Active ingredients:
Domperidone
Specification:
99%MIN
Testing Method:
HPLC
Appearance:
White powder
Domperidone is a novel peripheral dopamine receptor antagonist that does not cross the blood-brain barrier; anti-emetic. Domperidone(Motilium) is a dopamine blocker and an antidopaminergic reagent.

V2-Function1. Gastrointestinal problems

There is some evidence that domperidone has antiemetic activity. Domperidone is used, together with metoclopramide, cyclizine, and 5HT3 receptor antagonists (such as granisetron) in the treatment of nausea and vomiting.
It can be used in patients with Parkinson's disease because, unlike metoclopramide, domperidone does not cross the blood–brain barrier.
Domperidone has also been found effective in the treatment of gastroparesis, a stomach motility condition, and for paediatric gastroesophageal reflux (infant vomiting).
In Canada, the drug is indicated "for the symptomatic management of upper gastrointestinal motility disorders associated with chronic and subacute gastritis and diabetic gastroparesis." The drug may also be used "to prevent gastrointestinal symptoms associated with the use of dopamine agonist antiparkinsonian agents".
2. Lactation
The hormone prolactin stimulates lactation in humans, and its release is inhibited by the dopamine secreted by the hypothalamus. Domperidone, by acting as an anti-dopaminergic, results in increased prolactin secretion, and thus promotes lactation

Analysis

V2-Specification 

 

Items

Requirements

Results

Appearance

White to off white powder

White powder

Solubility

Practically insoluble in water, soluble in dimethylformamide, 

slightly soluble in ethanol(96%) and in methanol

Confirms

Identification

A. M.P. 244~248℃

244.5~245.5℃

B. IR should comply

Confirms

C. TLC should comply

Confirms

D. It gives the reaction of non-nitrogen substituted barbiturates.

Confirms

Related substance

Total impurities≤0.5%

≤0.29%

Individual impurity≤0.25%

≤0.18%

Loss on drying

≤0.5%

0.07%

Assay

99.0%~101.0%

99.49%

 

Packaging & Shipping

Package 1//sc01.alicdn.com/kf/H1126fb2c3a2a4891845938e6f0bc87f7N/238246835/H1126fb2c3a2a4891845938e6f0bc87f7N 

Company Information

Qingdao Sigma Chemical Co., Ltd.is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.

The aim of Qingdao Sigma Chemical Co., Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced
processing technology and it has gained a high and reliable reputation from customers at both quality and services.

 

Qingdao Sigma Chemical Co., Ltd has become the "Top 500 Chinese manufacturing companies",

"Top 20 of global chemical sales".Qingdao Sigma Chemical Co., Ltd has 21 subsidiaries and holding companies.

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Answer: Yes, we are factory founded on 2002.
 
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Q4:Can you give me a discount price?
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Q5:How can i get a sample?
free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
 
Q6: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
 
Q7:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

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