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Factory supply 99% l-5-methyltetrahydrofolate calcium / calcium l-5-methyltetrahydrofolate
1-9 Gram
$3.00
≥ 10 Gram
$1.00
- Item No.TOPMOQ1 Gram
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If over 500pcs, mass production will start until pre-production sample has been approved.
Est. 7 days production
The calcium salt of L-5-methyltetrahydrofolic acid which belongs to the group of folate vitamins (Vitamin B9, Folacin).
It is a coenzymated form of folic acid and a more bioavailable alternative in dietary supplements.
Items | Specifications | Results |
Appearance | White to yellow powder | White to yellow powder |
Assay(HPLC)L-isomer | 95.0%~103.0% | 98.60% |
Specific Rotation (C=1.5% in water, 25℃) | +38.0 to +42.0° | +38.5° |
Identification(IR;HPLC;Calcium) | IR spectrum /HPLC/ Calcium matches R.S. | Matches R.S. |
Calcium (Anhydrous basis) | 7.0~8.5% | 7.80% |
Chloride(Cl) | ≤0.5% | <0.1% |
Residue on ignition | ≤0.1% | 0.02% |
Arsenic (As2O2) | ≤1 ppm | <1ppm |
Boron | ≤20 ppm | <20ppm |
Heavy metals (as Pb) | ≤10 ppm | <10ppm |
Residual solvent(Ethanol) | ≤1000 ppm | <100 ppm |
Total plate count | ≤100 cfu/g | <10 cfu/g |
Yeast & Mold | ≤100 cfu/g | <10 cfu/g |
Salmonella | Negative | Complies |
E. Coil | Negative | Complies |
Conclusion: | The above items of the product conform to the standard. | |
1. Mainly for folic acid antagonists (such as methotrexate, pyrimethamine, benzyl cefalexin and trimethoprim) antidote, it's usually used for prevention of methotrexate dose or overdose treatment caused severe toxic effects.
2. Folic acid treatment of the following diseases, such as inflammatory diarrhea and protein-energy malnutrition (poor nutrition), pregnancy or infancy megaloblastic anemia caused by poor.
3. as adjuvant therapy for colon cancer, rectal cancer.
4. Combined with 5-FU and treatment of digestive tract tumors or other 5-FU-sensitive tumors. High-dose CF used in conjunction with 5-FU (LF), the basic programme is currently the treatment of colon and rectal cancer.
5. For children with leukemia, lymphoma, and osteosarcoma, such as high dose MTX treatment when rescued.
Qingdao Sigma Chemical Co.,Ltd is a global chemical industry manufacturers and suppliers of pharmaceuticals
and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
The aim of Qingdao Sigma Chemical Co.,Ltd is a quality policy that "Elements in the system
all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
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