^{Product Name: Ciclopirox Olamine}

^{Synonym: 6-Cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one 2-aminoethanol}

^{Purity: 99%min}

^{Appearance: White crystalline powder}

^{CAS No.: 41621-49-2
EINECS: 255-464-9}

^{Molecular formula: C14H24N2O3}

^{Molecular weight: 268.352}

<sup>Ring is a new kind of broad-spectrum pyrazole ketone amine topical antifungal drugs, pharmaceutical factory successfully developed by the federal Germany, mechanism of action is by changing the fungal cell membrane integrity, cause the outflow in the cell, and blocking the protein precursor uptake, led to the deaths of fungal cells, the skin tinea bacteria, yeast and mold have stronger bacteriostasis and sterilization effect, permeability is strong. In the higher concentration, there are also some inhibitory effects on various actinomycetes, gram-positive and gram-negative bacteria and mycoplasma, chlamydia, trichomonas, vaginal trichomonas and pseudomonas aeruginosa.

Compared with imidazoles antifungal agents, cyclopiramine has a strong permeability to the cuticle of the skin fungus, so it has significant bacteriostatic effects on the deep fungi of the cuticle, such as tinea.</sup>

 Pyridine ketones broad-spectrum antifungal agents, have inhibiting effects on a variety of skin fungi . They can prevent the substances necessary for Candida albicans cells survival such as amino acids, potassium ions, phosphate,going through the cell membrane ,which can cause by certain important matrix or intracellular ions failure,and then inhibit or kill fungal cells.

There are a wide range of anti-fungal effects, they can have a killing effect on the skin filamentous bacteria, yeast fungi , they have inhibition effects on a variety of Gram positive and negative bacteria, chlamydia, trichomoniasis, Proteus, E. coli, Pseudomonas and Staphylococcus bacteria. They are used to treat fungal skin disease, tinea versicolor, vulvovaginal Candida disease, skin and fingers (toe) candidiasis ,they have significant effects , and lower side effects.

Company Information

Qingdao Sigma chemical Co., Ltd is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
 
The aim of Qingdao Sigma chemical Co., Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.