GMP Factory supply API ISOTRETINOINe / Isotretinoine powder
10-99 Gram
$4.00
100 -999 Gram
$1.00
≥ 1000 Gram
$0.65
Choice
Quantity:

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If over 500pcs, mass production will start until pre-production sample has been approved.
Est. 7 days production

1)Product Name:Factory suppply Isotretinoin powder/retinoic acid powder CAS 4759-48-2
2)Appearance: An orange yellow or yellow, crystalline powder
3)Active ingredients: Isotretinoine
4)Specification:98.5%
5)Test method:HPLC
6)Introduction:
Isotretinoine (13-cis-Retinoic acid )is a vitamin A analog that inhibits cell proliferation and induces cell differentiation. Clinically, 13-cis-Retinoic acid is primarily used in the treatment of severe recalcitrant nodular acne. Its effects include reducing the production of sebum, shrinking the size of the sebaceous glands, stabilizing keratinization, preventing comedones from forming, and reducing inflammation of inflammatory acne. Though the exact mechanism of action of 13-cis-Retinoic acid is not fully understood, studies have suggested that the compound alters DNA transcription and induces apoptosis in select types of cells throughout the body.
Test/Observation | Specifications | Result |
Assay Content HPLC | 97%-102% | 99.12% |
Appearance | Fine Powder | Complies |
Identification | IR. UV | Complies |
Odor | Characteristic | Complies |
Mesh | 100% pass 100 mesh | Complies |
Residue on ignition | MAX 0.1% | Complies |
Loss on drying % | MAX 0.5% | 0.39% |
Ash % | MAX. 1.0% | 0.52% |
Heavy metals PPM | MAX. 0.002% | Complies |
Limit of Isotretinoin | MAX5.0% | 3.9% |
Organic Volatile Impurities | Meet The Requirements | Complies |
Microbiology Total Plate Count Yeast & Mold E. Coli Salmonella | < 1000cfu/g < 100cfu/g Negative Negative | 82cfu/g Negative Complies Complies |
Qingdao Sigma chemical Co., Ltd is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
The aim of Qingdao Sigma chemical Co., Ltd is a quality policy that"Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.


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