Product name: Diclofenac sodium

CAS:15307-79-6

MF:C14H10Cl2NNaO2

MW:318.13

Appearance:White  or slightly  crystalline powder

Assay:99%Min

Loss on drying:0.2 %

Heavy metals:Less than 10ppm

Package:25kg/drum

Application: Antibiotic and Antimicrobial Agents

Diclofenac Sodium is the salt form of diclofenac, an active metabolite of the NSAID aceclofenac (sc-217557). Hydrolysis of aceclofenac, an inhibitor of interleukin-1B-induced prostaglandin E2 production with no inhibitory activity against Cox (cyclooxygenase), generates diclofenac, an inhibitor of both Cox-1 and Cox-2. Oxidation of diclofenac produces the metabolite

4'-hydroxy diclofenac (sc-202423) which demonstrates specific inhibition of Cox-2. Inhibition of Cox by diclofenac and 4'-hydroxy diclofenac suppresses prostaglandin E2 synthesis, producing antiinflammatory and analgesic effects. Diclofenac is also shown to stabilize the native tetrameric conformation of transthyretin (TTR) fibrils, preventing the formation of insoluble amyloidogenic TTR deposits. Diclofenac Sodium is a substrate of CYP2C9.

1. It is used to relieve the swelling and pain symptoms of rheumatoid arthritis, osteoarthritis, spinal arthropathy, gout arthritis, rheumatoid arthritis and other arthritis.

2. It is used to treat rheumatic pain of all kinds of non-articular soft tissues, such as shoulder pain, tenosynovitis, bursitis, muscle pain and post-exercise injury pain, etc.;

3. Used for acute mild and moderate pain, such as after surgery, after trauma, after labor injury, dysmenorrhea, toothache, headache, etc.; It has certain antipyretic effect on heat.

Qingdao Sigma Chemical Co., Ltd.is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.

The aim of Qingdao Sigma Chemical Co., Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.

Qingdao Sigma Chemical Co., Ltd has become the "Top 500 Chinese manufacturing companies",

"Top 20 of global chemical sales".Qingdao Sigma Chemical Co., Ltdhas 21 subsidiaries and holding companies.

Q1: Are you a manufacturer?
Answer: Yes, we are factory founded on 2002.
 
Q2: How to contact with us?
Click the Alibaba "Contact Supplier" And then send us message the product you interest in, you will get reply within 24 hours.
 
Q3:Which kind of payment terms do you accept?
For small order,you can pay by T/T,Western Union or Paypal,nomal order by T/T to our company account
 
Q4:Can you give me a discount price?
Surely,It depend on your qty
 
Q5:How can i get a sample?
free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
 
Q6: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
 
Q7:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.