High Purity CAS 198470-85-8 parecoxib sodium
1-1000 Kilogram
$100.00
≥ 1001 Kilogram
$10.00
- Item No.parecoxib sodiumMOQ1 Kilogram
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If over 500pcs, mass production will start until pre-production sample has been approved.
Est. 7 days production
CAS NO.: 198470-84-7 Synonyms: n-(4-(5-methyl-3-phenyloxazol-4-yl)phenyl)sulfonylpropanamide MF: C19H18N2O4S MW: 370.422 InChI: 1S\/C19H18N2O4S\/c1-3-17(22)21-26(23,24)16-11-9-14(10-12-16)18-13(2)25-20-19(18)15-7-5-4-6-8-15\/h4-12H,3H2,1-2H3,(H,21,22) Melting point: 148.9~151.0℃ Appearance:white crystalline powder Specification:99%min Standard: EP/BP/USP Odor: odorless |
Parecoxib is a water soluble and injectable prodrug of valdecoxib. It is marketed as Dynastat in the European Union. Parecoxib is a COX2 selective inhibitor in the same category as celecoxib (Celebrex) and rofecoxib (Vioxx). As it is injectable, it can be used perioperatively when patients are unable to take oral medications. It is approved through much of Europe for short term perioperative pain control much in the same way ketorolac(Toradol) is used in the United States. However, unlike ketorolac, parecoxib has no effect on platelet function and therefore does not promote bleeding during or after surgery. In addition, ketorolac has a much higher gastrointestinal toxicity profile compared to most other nonsteroidal antiinflammatory drugs (NSAIDs) including ibuprofen and naprosyn. However, in the United States ketorolac is the only injectable NSAID, although it is banned in many European countries due to concerns about surgical bleeding and stomach ulcers after surgery.
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