Cas:72909-34-3 Color:Red to Purple Purity:98% Species:synthesize Suggested Use:10~20mg daily Molecular Form:C14H6N2O8 Certificate: ISO,.,HALAL,KOSHER

Pyrroloquinoline quinone (henceforth PQQ) is a small quinone molecule which has the ability to be a REDOX agent, capable of reducing oxidants (an antioxidant effect) and then being recycled by glutathione back into an active form. It appears to be quite stable as it can undergo several thousand cycles before being used up, and it is novel since it associates with protein structures inside the cell (some antioxidants, mostly notably carotenoids like β-carotene and Astaxanthin, are located at specific areas of a cell where they exert proportionally more antioxidant effects due to proximity; PQQ seems to do this near proteins like carotenoids do so at the cell membrane).

PQQ is present in nanomolar quantities in most foods and in most animal tissuse. It promotes growth, mitochondrial function, and development in vivo and stimulates cell proliferation and viability in culture. It is a potent antioxidant that scavenges superoxide and peroxinitrite. It is neuroprotectant against 6-hydroxydopamine-induced and hypoxia/ischemia-induced neurotoxicity. PQQ conjugates to α-synuclein in vitro, inhibiting the formation of amyloid fibrils.

1.Improve the body's immune function

As a necessary factor of human development, it can stimulate the growth of cells in the body, especially the activation of human B cells, T cells, antibody production, improve the immune function of human body.PQQ is the most powerful bioactive substances so far.

2. Prevent and treat the liver damage

Can significantly reduce serum bilirubin, alanine aminotransferase levels, make liver function normal, regulate liver damage and have very good curative effect on liver disease.

3. Reduce free radical damage to human body

PQQ is a kind of oxidoreductase prosthetic group, involved in biological REDOX reaction in the body, can effectively remove free radicals in the body, reduce the harm of human body free radical, protect tissues, reduce the body damage caused by various diseases, such as heart disease, cancer and all kinds of inflammation.Free radicals is the source of diseases.

4. Regulate various neurological diseases

PQQ is a new kind of water-soluble vitamins, can promote the synthesis of neural factors in the human body, regulate various neurological diseases.

5. Promote the absorption of amino acids

PQQ is the prosthetic group of quinone protease, participate in the respiratory electron transport chain, in the human body through the effect of glucose, can promote the absorption of amino acids.Amino acid composition of cell SAP and synthetic protein peptide is the main raw material, is an important part of the body's biological active substances.

6. Promote the synthesis of growth factors

Growth factor is the human growth hormone, stimulate biological growth, can stimulate human body cell growth, increase the cell density.Trace amounts of PQQ could improve the biological function of the organization's ability to metabolize and growth.Why can slow the aging?

 It means PQQ may have the power to help protect brain function well into our advanced years. Initial evidence of this was demonstrated in a 2009 study published in the medical journal Food Style.1 In this double-blind, placebo-controlled study, 71 men and women aged 45-65 consumed foods fortified with 20 mg of PQQ (as found in our new maximum potency formula), PQQ plus CoQ10, or placebo, for 12 weeks. Throughout the study, subjects participated in cognitive tests designed to measure memory, recall and cerebral function. The graph shown illustrates the results. Similar results were reported in a 2011 follow-up study in which PQQ was given directly as a supplement.

Qingdao Sigma Chemical Co., Ltd.is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.

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