Dapoxetine(dapoxetine) as a new fast SSRI, a short half life, a selective 5 - HT reuptake inhibitor (SSRI), for the treatment of premature ejaculation and erectile dysfunction. Dapoxetine is a selective 5 - HT reuptake inhibitor, such drugs widely used to treat depression and related affective disorders.

To treat male premature ejaculation and erectile dysfunction. Waldinger's meta-analysis shows that the use of these conventional antidepressants increasing IELT from two to ninefold above baseline in comparison of three to eightfold when dapoxetine is used. Dapoxetine, on the other hand, is a fast-acting SSRI. It is rapidly absorbed and eliminated from the body within a few hours. This favorable pharmacokinetics minimizes the risk of the drug's accumulation in the body, and therefore reducing side effects.

For erectile dysfunction, vardenafil may be effective in the treatment of premature ejaculation, where it may significantly increase the time from penetration to ejaculation.

(1)Dapoxetine is the only approved medication to treat premature ejaculation.

(2)It is absorbed by stomach, and can be effected after 30-60mins, lasts for several dasy, without side-effect, can't be detected, accompanying light headache, sick, but can disappear soon.

(3)advantages: less dose,rapid onset, long half life and safety.

Premature ejaculation is a common problem among men, and research suggests that a third of men suffer from this sexual dysfunction at one time or another. It is more common than erectile dysfunction (the inability to maintain an erection). For some men, premature ejaculation is frequent enough to cripple their sex lives. Dapoxetine hydrochloride is the first pharmaceutical approach for treating premature ejaculation that has shown some degree of success.

Treat male premature ejaculation and erectile dysfunction.Dapoxetine, marketed as (among and other brands) is the first compound developed specially for the treatment of premature ejaculation (PE) for men at th age of 18-64 years old. Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin's action at the post synaptic cleft, so as to delay ejaculation.. As a member of selective serotonin reuptake inhibitor (SSRI) family, Dapoxetine was initially created as an antidepressant. However, unlike other SSRIs, Dapoxetine is absorbed and eliminated rapidly in the body. Its fast response makes it suitable for the treatment of PE but not as an antidepressant.