High quality Lapatinib ditosylate with best price 388082-78-8



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High quality Lapatinib ditosylate with best price 388082-78-8
High quality Lapatinib ditosylate with best price 388082-78-8
High quality Lapatinib ditosylate with best price 388082-78-8
High quality Lapatinib ditosylate with best price 388082-78-8
High quality Lapatinib ditosylate with best price 388082-78-8
High quality Lapatinib ditosylate with best price 388082-78-8
High quality Lapatinib ditosylate with best price 388082-78-8

High quality Lapatinib ditosylate with best price 388082-78-8

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From $700.00450.00 / Kilogram
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If over 500pcs, mass production will start until pre-production sample has been approved.

Est. 7 days production

Product Description

    Product Description

Lapatinib produced by glaxosmithkline. Epidermal growth factor receptor tyrosine kinase inhibitor, an oral administration of small molecules. Mainly used for joint card of capecitabine in the treatment of erbB-2 overexpression, who previously received including anthracyclines and paclitaxel and trastuzumab (Herceptin) in the treatment of advanced or metastatic breast cancer. When taking the need to pay attention to its adverse reactions.


 In the experiment of Chinese hamster, no carcinogenic effect was found, and no genetic toxicity was found. There was no effect on mating ability and fertility of rats under high dose. There are 1 cases reported in pregnant women in March before taking lapatinib, full-term pregnancy after the birth of healthy children .
 Lapatinib in Indonesia and capecitabine combination in the treatment of breast cancer, the effect is better, and of anthracene ring antibiotics, taxanes and trastuzumab resistant patients effective, mild side effects, for advanced or metastatic breast cancer patients and a drug treatment.


   Certification of Analysis

Name: Lapatinib Ditosylate

CAS No.:







A white,Crystalline Powder





Molecular Weight






Loss on Drying:



Residue on ignition:



Boiling Point:

750.7°C at 760 mmHg


Flash(ing) point:




at -20°C 2 years 


Heavy Metals:



Acidity or Alkalinity:






Readily Carbonizable Substances:



Ordinary Impurities:






Lapatinib is a targeted therapy of breast cancer drug, is a tyrosine kinase inhibitor, can effectively inhibit the human epidermal growth factor receptor -1 (ErbB1) and human epidermal growth factor receptor (ErbB2) tyrosine kinase activity of -2. It is unique in that it can play a role in a variety of ways, so that breast cancer cells can not receive the signal needed for growth. The mechanism of action is to inhibit the intracellular EGFR (ErbB-1) and HER2 (ErbB-2) ATP sites to prevent phosphorylation and activation of tumor cells, and to block the down-regulation of signaling by EGFR (ErbB-1) and HER2 (ErbB-1) homogeneous and heterogeneous two aggregates.
Molecular targeted therapy for breast cancer is the treatment of oncogenes and related expression products related to the occurrence and development of breast cancer. Molecular targeted drugs control cell gene expression by blocking the signal transduction of tumor cells or related cells, thereby inhibiting or killing tumor cells.

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Company Information

Qingdao Sigma chemical Co., Ltd is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
The aim of Qingdao Sigma chemical Co., Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.


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Q1: Are you a manufacturer?
Answer: Yes, we are factory founded on 2002.
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Q3:Which kind of payment terms do you accept?
For small order,you can pay by T/T,Western Union or Paypal,nomal order by T/T to our company account
Q4:Can you give me a discount price?
Surely,It depend on your qty
Q5:How can i get a sample?
free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
Q6: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q7:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
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