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Hot selling high quality Dilthiazem hydrochloride 33286-22-5 with reasonable price and fast delivery !!
1-1000 Kilogram
$140.00
≥ 1001 Kilogram
$50.00
- Item No.TOPMOQ1 Kilogram
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If over 500pcs, mass production will start until pre-production sample has been approved.
Est. 7 days production
| Items | Standard | ||
| Character | White or almost white crystalline powder | ||
| Identification | Positive | ||
| Residue on ignition | ≤0.5% | ||
| Heavy metals | NMT 20ppm | ||
| Arsenic | NMT 5ppm | ||
| Sulphated ash | NMT 0.1% | ||
| Loss on drying | NMT 0.5% | ||
| Total impurities | NMT 1.5% | ||
| Assay(HPLC) | 97%-103% |
Diltiazem is a nondihydropyridines calcium channel blocker used in the treatment of hypertension,angina pectoris, and some types of arrhythmia. It relaxes the smooth muscles in the walls of arteries, which opens (dilates) the arteries, allows blood to flow more easily, and lowers blood pressure. Additionally, it lowers blood pressure by acting on the heart itself to reduce the rate, strength, and conduction speed of each beat.
It is also used off-label as an effective preventive medication for migraine. It is a class 3 antianginal drug, and a class IV antiarrhythmic.
Diltiazem is a potent vasodilator, increasing blood flow and variably decreasing the heart rate via strong depression of A-V node conduction. Its pharmacological activity is somewhat similar to verapamil, another nondihydropyridine (non-DHP) calcium channel blocker.Chemically, it is based upon a 1,4-thiazepine ring making it a benzothiazepine-type calcium channel blocker.
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