Hot selling high quality Glibenclamide 10238-21-8 with reasonable price and fast delivery !!
1-9 Kilogram
$78.60
≥ 10 Kilogram
$71.50
- Item No. SM842MOQ 1 Kilogram
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If over 500pcs, mass production will start until pre-production sample has been approved.
Est. 7 days production
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High quality Glibenclamide 10238-21-8
1.Competitive price
2.Fast Delivery Within 2 days
3.SGS , BV, GMP,ISO approve
4.Professional factory
Hypoglycaemic. Inhibit decomposition of glycogen and Gluconeogenesis, reduce glucoses production and output in liver;Besides, it can strengthen pancreass sensitivity to insulin and consume more sugar,reducingFPG and P2hPG. For the second-generation sulfonylurea drugs, there is a strong role in lowering blood glucose, its hypoglycemic effect than D-860 Strong 100-fold. Fasting blood glucose after treatmentcompared with postprandial blood glucose significantly decreased, respectively, reduced by about 35%, and 21% or less.Easily absorbed from the gastrointestinal tract, plasma protein binding rate is high.Fall bloodsugar function strong, Glyburide capsule: its role a toluene sulfonylurea urea butyl 100 times stronger. Oral 30 minutes later appeared for about 16 ~ role 24 hours. Easily absorbed from the gastrointestinal tract, plasma protein binding rate is high. T1/2 about 10 h. Almost all by hepatic metabolism, the main metabolites hypoglycemic activity is weak. About 50% of metabolites from urine discharge, and another 50% by bile into debris.
Glyburide piece: this product is lowering blood sugar pills. 1. Stimulate pancreatic beta cells secrete insulin, a prerequisite, there is still a beta cell synthesis and secretion of insulin function; Through the increase insulin
levels for the liver or portal vein direct action, inhibit liver glycogen decomposition and glycogen vision, liver function was born generation and output glucose reduced; 3. Also may increase the organization for pancreatic insulin sensitiity and sugar (mainly through the use of possible receptors, therefore, the role) function is reduced fasting blood sugar and blood glucose after a meal.
ITEM | STANDARD | RESULTS |
Appearance | Crystalline powder | Conforms |
Melting range | 129°C~132°C | 130.8°C-131°C |
Loss on drying | ≤0.5% | 0.20 % |
Specific rotation | -58°~-62°(C=1,in CH3OH) | -61.05° |
Sulphated ash | ≤0.1% | 0.08 % |
Heavy metals | ≤10ppm | Conforms |
Chlorides | ≤0.02% | Conforms |
Sulfates | ≤0.02% | Conforms |
Fluorine | 14.7%~17.9% | 15.2% |
Residual solvent | Methanol ≤0.2% Isopropanol ≤0.2% Ethyl acetate≤0.2% Chloroform ≤0.2% | 0.0% 0.0% 0.0% 0.0% |
Related substances (HPLC) | Single impurity ≤0.2% Total impurities ≤0.5% | 0.05% 0.08% |
Assay | ≥99.5% | 99.92% |
Conclusion | Accordance with the reference |
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Qingdao XIGRMA Chemical Co., Ltd. Import And Export Co., Ltd is is a global chemical industry manufacturers
and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals
and fine chemicals etc.The aim of XIGRMA is a quality policy that "Elements in the system all have been satisfied,
Personnel has been trained; Every batch of material is checked,
Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time,
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The quality, colors and forms of our products have reached a high level in related chemical industry,
which relies on characteristic and advanced processing technology and it has gained a high
and reliable reputation from customers at both quality and services.
XIGRMA has become the "Top 500 Chinese manufacturing companies","Top 20 of global chemical sales".
XIGRMA has 21 subsidiaries and holding companies.
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