English name: Trifluoperazine dihydrochloride

Content: 99%

CAS: 440-17-5

Packing: 25kg cardboard drum

Product Details

Molecular formula: C21H25ClF3N3S

Molecular weight: 443.9565

 Trifluoperazine Dihydrochloride is a cell-permeable phenothiazine compound with antiadrenergic effects. Trifluoperazine is described as an antagonist of adrenergic receptors, demonstrating much higher activity at the α-1 over the α-2 adrenergic receptor. Trifluoperazine is also described to produce antidopaminergic effects. Trifluoperazine facilitates agonist induced elevation of cytosolic calcium at low concentrations (10μM), and antagonizes CaM (calmodulin) at higher concentrations. Potent and irreversible inhibitor of cAMP-gated cationic channels. Inhibits DNA repair. Potent neurotoxin. Trifluoperazine is an inhibitor of D2DR.

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