Trifluoperazine Dihydrochloride is a cell-permeable phenothiazine compound with antiadrenergic effects. Trifluoperazine is described as an antagonist of adrenergic receptors, demonstrating much higher activity at the α-1 over the α-2 adrenergic receptor. Trifluoperazine is also described to produce antidopaminergic effects. Trifluoperazine facilitates agonist induced elevation of cytosolic calcium at low concentrations (10μM), and antagonizes CaM (calmodulin) at higher concentrations. Potent and irreversible inhibitor of cAMP-gated cationic channels. Inhibits DNA repair. Potent neurotoxin. Trifluoperazine is an inhibitor of D2DR.
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Qingdao Sigma Chemical Co., Ltd.is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
The aim of Qingdao Sigma Chemical Co., Ltdis a quality policy that"Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.