| Quick Details |
| Place of Origin ||CN;SHN|
|Usage|| Animal Pharmaceuticals |
| Brand Name ||xigema|
| Model Number ||99%|
|solubility|| H2O: 10 mg/mL |
| storage temp. ||2-8°C|
| Melting point || 267 °C (dec.)(lit.) |
| Grade Standard || Medicine Grade |
|Type|| Vitamins, Amino Acids and Coenzymes |
| CAS No. ||143-67-9|
| Other Names || Vinblastine sulfate |
| EINECS No. ||205-606-0|
Vinblastine sulfate 143-67-9
2.Fast Delivery Within 2 days
3.SGS , BV, GMP,ISO approve
product of description
Product Name: Vinblastine Sulfate
Synonyms: Vinblastine, Vinblastine Sulphate, Vinblastine sulfate salt, Vinblastinum
Molecular Formula: C46H60N4O13S
Molecular Weight: 909.05
CAS NO: 143-67-9
Grade Standard: Pharma Grade
Purity: high purity
Certification: ISO9001, GMP
Quality Specification:USP36 EP7.0
It is an anti-cancer drug. it can be used for the treatment of hodgkin's disease and chorio-epithelioma,lymphosarcoma, acute leukemia and breast cancer, etc.
Packaging & Delivery:
Protect from light, tightly sealed, freezer storage(leiss than -20℃).
Delivery Detail:prompt shipment.
|Other Name||VINBLASTINE SULFATE|
|MP||267 °C (dec.)(lit.)|
|Usage||Antineoplastic agents; API|
Pharmacology and toxicology
Changchun alkali is a kind of alkaloid that has anticancer activity. It mainly inhibits the polymerization of microtubules and prevents the formation of microtubules of the spindle, which stops mitosis in the medium term. It can also be applied to cell membrane, interfering with the transport of amino acids by cell membrane, which can inhibit protein synthesis and inhibit RNA synthesis. Vinblastine antineoplastic spectrum broad, in 0.05 ~ 0.1 mg/kg doses in mice L1210 leukemia, airy, S180 ascites carcinoma, C3H mice spontaneous and metastatic breast cancer have obvious anti-tumor activity, to transplantation in rat cheek pouch of wool also has inhibitory effect on the growth of cancer cells.
Oral absorption is poor and requires intravenous administration. After the injection of changchun base, it was rapidly distributed in various tissues, rarely penetrating the blood-brain barrier, and the protein binding rate was 75%. Blood was used to remove the drug in two directions, with t1/2 alpha for 4.5 minutes, t1/2 beta for 190 minutes, and the tip elimination phase t1/2 gamma for 24 hours. In the liver, most of it was excreted with bile, and 33% of the drug was excreted in the feces within 3 days after use, mainly metabolites, and 21 percent were excreted with urine.
Mainly used for the treatment of solid tumors. The efficacy of malignant lymphoma, testicular tumor and choriocarcinoma is better, and it also has some effect on lung cancer, breast cancer, ovarian cancer, skin cancer, renal cell tumor and monocyte leukemia.
Hodgkin's disease and malignant lymphoma can also be used to treat chorionic epithelial carcinoma and breast cancer.
why choose us:
Our products meet MSDS safe standard and we have ISO and other certificate so yan can get high quality products from our company.
We are the company which is the joint of trade and industry so we cao provide the competitive price and high quality product.
We can do according to the customers' request.
The products can be transported by Courier, by air or by sea.
We offer specialized logistic service including export declaration,customs clearance and every detail during shipment,this makes us able to offer you one-stop service from the order to the products transported to your hand.
QingdaoxigemaCHEMICAL Co., Ltd is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
The aim of xigema is a quality policy that"Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
xigema has become the"Top 500 Chinese manufacturing companies","Top 20 of global agrochemical sales". xigema has 21 subsidiaries and holding companies.