Molecular formula: C20H34O5
Molecular weight: 354.48
CAS: 745-65-3
EINECS: 212-017-2
Melting point: 115-116ºC

Water-soluble: insoluble

The prostaglandins (PG) are a group of physiologically active lipid compounds having diverse hormone-like effects in animals. Prostaglandins have been found in almost every tissue in humans and other animals. They are derived enzymatically from fatty acids. Every prostaglandin contains 20 carbon atoms, including a 5-carbon ring. They are a subclass of eicosanoids and of the prostanoid class of fatty acid derivatives.

1. Treatment of hepatitis cirrhosis, cerebral infarction, diabetes, impotence, respiratory disease. Damage to liver function is not serious childA, B-class patients, especially childA-class patients have anti-fiber effect. For induction of labor, oxytocin, renal insufficiency, treatment of mumps, pancreatitis and so on. Prostaglandin E1 is mainly used for myocardial infarction, heart failure, thrombotic vasculitis, chronic arterial occlusive disease, central retinal vein thrombosis, for cardiopulmonary bypass to protect platelets, arterial angiography, revascularization surgery.
2. Derivatives of peanut tetraene. Can significantly inhibit and release platelet aggregation, improve blood microcirculation, but also directly on the role of vascular smooth muscle, dilation of arteries, half-life of up to 5 to 10 minutes. Clinical use for all types of angina, reduce myocardial infarct size, maintenance of infant arterial duct opening, arterial and pulmonary hypertension, peripheral vascular disease and other forms of anticoagulation in the treatment of cardiopulmonary bypass.
3. For myocardial infarction, heart failure, thrombotic vasculitis, chronic arterial occlusion, retinal central venous thrombosis and so on.

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