Hot selling high quality baclofen powder with CAS 1134-47-0
100 -999 Pieces
≥ 1000 Pieces
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If over 500pcs, mass production will start until pre-production sample has been approved.
Est. 7 days production
|Place of Origin||CN;SHN|
|Application||Pharmaceutical Raw Intermediates|
|Shelf Life||2 Years|
|Grade Standard||Medicine Grade|
|Type||Vitamins, Amino Acids and Coenzymes|
Packaging & Delivery
- Selling Units:
- Lead Time:
Quantity(Gram) 1 - 1000 >1000 Est. Time(days) 3 To be negotiated
Baclofen is a derivative of GABA and a selective agonist of the GABAB receptor. The GABAB receptors are G-protein-coupled metabotropic proteins responsible for depression of synaptic transmission and inhibition of neuronal excitability, distinct from the GABAA and GABAC ionotropic receptors responsible for fast neuronal response. As one of the only identified molecules with specificity for the GABAB receptor, Baclofen has been widely employed in elucidating the function and behavior of these receptors. Agonism of GABAB by Baclofen was initially identified to produce muscle relaxation and relief of muscle spasm. Modulation of the GABAB receptor by agonists has been correlated to reduction of reinforcing effects in addictions. Recently the GABAB receptors have been identified as modulators of transient lower esophageal relaxations, a molecular underpinning of gastroesophageal reflux disease. Baclofen provides a prototypic structure for design of GABAB agonists to differentially modulate the behavior of the GABA system.
Baclofen can inhibit the hypothalamic prostaglandin synthesis and release, body temperature regulation center experience to restore the normal response of neurons in the sky cooling effect
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Qingdao Sigma Chemical Co., Ltd.is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
The aim of Qingdao Sigma Chemical Co., Ltd is a quality policy that"Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
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