Hot selling high quality mycophenolic acid with reasonable price 24280-93-1
1-9 Kilogram
$130.00
≥ 10 Kilogram
$119.10
- Item No. TOPMOQ 1 Kilogram
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1)Product Name:Supply High purity and best price of Mycophenolic acid powder
2)Appearance:White crystalline powder
3)Specification:99%
4)Introduction:
Mycophenolic acid is an immunosuppressant drug used to prevent rejection inorgan transplantation. It was initially marketed as the prodrug mycophenolate mofetil (MMF) to improve oral bioavailability. More recently, the salt mycophenolate sodium has also been introduced. Mycophenolic acid is commonly marketed.
Item | Specifications | Results | |
Appearance | White or almost white crystalline powder | Almost white, crystalline powder | |
Identification | IR | IR spectrum exhibits maxima at the critical wavelengths observed for a similar preparation of a standard. | Conforms |
HPLC | The RT matches that observed for the chromatographic analysis of the standard | Conforms | |
Loss on drying | ≤1.0% | 0.08% | |
Heavy metal | ≤20ppm | <20ppm | |
Residual on Ignition | ≤0.1% | 0.03% | |
Individual Impurity | ≤0.5% | 0.12% | |
Total impurity | ≤3.0% | 0.73% | |
Assay(on the dried basis) | 97.0%~101.0% | 98.6% | |
Residual Butyl Acetate | ≤0.5% | 0.09% | |
Conclusion | The results conforms with In-house standards |
Mycophenolic Acid is an immunosuppressant small molecule isolated as a fermentation product from several Penicillium species. Mycophenolic Acid functions as a potent reversible inhibitor of IMPDH (inosine monophosphate dehydrogenase), leading to a depletion of GMP in the cell and interruption of the de novo synthesis of purines necessary for lymphocyte proliferation. This powerful immunosuppressant property has been exploited in studies on organ transplant survival, rhuematoid arthritis, and psoriasis. Derivitization of Mycophenolic Acid to the morpholinoethyl ester, known as Mycophenolate mofetil (sc-200971), presents a greater bioavailability for the active compound.
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