Hot selling top quality Gentamycine Sulphate , CAS 1405-41-0 with best price and fast delivery!!

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Hot selling top quality Gentamycine Sulphate , CAS 1405-41-0 with best price and fast delivery!!
Hot selling top quality Gentamycine Sulphate , CAS 1405-41-0 with best price and fast delivery!!
Hot selling top quality Gentamycine Sulphate , CAS 1405-41-0 with best price and fast delivery!!
Hot selling top quality Gentamycine Sulphate , CAS 1405-41-0 with best price and fast delivery!!
Hot selling top quality Gentamycine Sulphate , CAS 1405-41-0 with best price and fast delivery!!
Hot selling top quality Gentamycine Sulphate , CAS 1405-41-0 with best price and fast delivery!!
Hot selling top quality Gentamycine Sulphate , CAS 1405-41-0 with best price and fast delivery!!

Hot selling top quality Gentamycine Sulphate , CAS 1405-41-0 with best price and fast delivery!!

  • Item No.99%
    MOQ1 Kilogram
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From $130.00128.00 / Kilogram
$130.00
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If over 500pcs, mass production will start until pre-production sample has been approved.

Est. 7 days production

 

 

 

 

ItemSpecificationsResults
CharacteristicA white or almost white powderConform
Identification(C/D) According to BP2002Conform
Color of solution≤6#Conform
PH3.5~5.55.18
Specific optical rotation10%(w/v) Water solution+116°
 +107°~+121°
Sulphate ash≤1.0%0.40%
Sulphated32.0~35.0%34.80%
Water≤15.0%10.60%
Bacterial endotoxin≤1.67EU/mgConform
Compostion C125.0~50.0%26.40%
Compostion C1a10.0~35.0%23.90%
Compostion C2+C2a25.0~55.0%49.80%
Assay≥590IU/mg629IU/mg
ConclusionThe results conforms with BP2002 standards
 

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Gentamycin sulfate is a kind of aminoglycoside drug, which ACTS on the ribosome in the bacteria, inhibits the synthesis of bacterial proteins, and destroys the integrity of bacterial cell membrane. This medicine can first hole by passive diffusion through the cell's outer membrane proteins, and then by the transportation system, through the cell membrane into the cell is not reversible to combine to the separation of the 30 s subunit ribosomal, causes the destruction of A bit, then:

(1) prevent the correct positioning of aminoacyl tRNA in A bit, especially the binding of methionyl tRNA, which interferes with the assembly of functional ribosomes and inhibits the formation of the 70s initiation complex.

(2) induced tRNA matching with triplet mRNA password mistake, lead to complete the 30 s subunit ribosomal wrong read the genetic code, error caused by amino acid into the protein structure, result in abnormal, without a functional protein synthesis.

(3) inhibit the combination of termination factor and A, so that the synthesized peptide chain cannot be released and prevent the complete ribosomal dissociation.

(4) preventing the polymerization and assembly process of polyribosomes, resulting in the depletion of ribosomes in bacteria.

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Company Information

Qingdao Sigma chemical Co., Ltd is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
 
The aim of Qingdao Sigma chemical Co., Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.

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