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ISO Factory supply 99% purity Tranilast with reasonable price CAS: 53902-12-8
1-999 Kilogram
$566.00
≥ 1000 Kilogram
$565.00
- Item No.99%MOQ1 Kilogram
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If over 500pcs, mass production will start until pre-production sample has been approved.
Est. 7 days production
ISO Factory supply 99% purity Tranilast
| Product Name: | Tranilast |
| Synonyms: | 2-[[3-(3,4-DIMETHOXYPHENYL)-1-OXO-2-PROPENYL]AMINO] BENZOIC ACID;TRANILAST;2-((3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl)amino)-benzoicaci;n-(3,4-dimethoxycinnamoyl)-anthranilicaci;n-5’;rizaben;SB-252218;N-(3',4'-DIMETHOXYCINNAMOYL)ANTHRANILIC ACID |
| CAS: | 53902-12-8 |
| MF: | C18H17NO5 |
| MW: | 327.33 |
| EINECS: | |
| Product Categories: | Angiotensin;Angiogenesis and Metastasis;Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;PEXID;Inhibitors |
| Mol File: | 53902-12-8.mol |
Items | Specification |
Appearance | Light yellow or light-yellow green crystal or crystalline powder |
Assay | ≥98.5% |
Melting point | 207-210°C |
Identification: | 1) It appears positive reaction 2) Maximum absorbability at 333nm Wavelength Minimum absorbability at 263nm Wavelength 3) Complies |
Chloride | Conform |
Relevant material | Conform |
Loss on drying | ≤0.5% |
Residue on ignition | ≤0.1% |
Heavy metals | ≤15ppm |
Microbe limitation | Conform |
Tranilast is a compound that exhibits anti-inflammatory and immunomodulatory effects by inhibiting lipid mediator and cytokine release from inflammatory cells and interfering with PDGF- and TGF-β1-induced proliferation and migration of vascular medial smooth muscle cells. Tranilast suppresses production of prostaglandin D2 (IC50 = 0.1 mM), prostaglandin E2 (IC50 = ~1-20 μM), thromboxane B2 (IC50 = ~10-50 μM), TGF-β1 (IC50 = ~100-200 μM), and interleukin-8 (IC50 = ~100 μM) in in vitro models as well as attenuates of the proinflammatory activity of human monocytes. While originally marketed as an antiallergenic drug, the efficacy of tranilast in preventing restenosis after percutaneous coronary intervention has been tested in a large-scale clinical trial. Additionally, tranilast inhibits VEGF-induced angiogenetic activities (i.e., proliferation, migration and tube formation of vascular endothelial cells) with IC50 values of 22, 18 and 193 μM, which may prove therapeutic for various retinal diseases.[Cayman Chemical]
The aim of Xigema is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
Xigema has become the "Top 500 Chinese manufacturing companies","Top 20 of global chemical sales".Xigema has 21 subsidiaries and holding companies.
Answer: Yes, we are factory founded on 2002.
Q2: How to contact with us?
Click the Alibaba "Contact Supplier" And then send us message the product you interest in, you will get reply within 24 hours.
Q3:Which kind of payment terms do you accept?
For small order,you can pay by T/T,Western Union or Paypal,nomal order by T/T to our company account
Q4:Can you give me a discount price?
Surely,It depend on your qty
Q5:How can i get a sample?
free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
Q6: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q7:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
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