ISO Factory supply 99% purity Tranilast with reasonable price CAS: 53902-12-8

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ISO Factory supply 99% purity Tranilast with reasonable price CAS: 53902-12-8
ISO Factory supply 99% purity Tranilast with reasonable price CAS: 53902-12-8
ISO Factory supply 99% purity Tranilast with reasonable price CAS: 53902-12-8
ISO Factory supply 99% purity Tranilast with reasonable price CAS: 53902-12-8
ISO Factory supply 99% purity Tranilast with reasonable price CAS: 53902-12-8
ISO Factory supply 99% purity Tranilast with reasonable price CAS: 53902-12-8

ISO Factory supply 99% purity Tranilast with reasonable price CAS: 53902-12-8

  • Item No.99%
    MOQ1 Kilogram
Tag  sourcing
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From $566.00565.00 / Kilogram
$566.00
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If over 500pcs, mass production will start until pre-production sample has been approved.

Est. 7 days production

Quick Details
Product name Tranilast
Appearance: White Powder
Place of Origin CN;SHN
Usage Animal Pharmaceuticals
Brand Name QDXIGEMA
Model Number 99%
Application Pharm Intermediates
CAS53902-12-8
solubility DMSO: 18 mg/mL
Color white to beige
storage temp. 2-8°C
Melting point 166.2-168.2 °C(lit.)
Merck14,9570
Purity:99%
Grade Standard Medicine Grade
Type Respiratory System Agents
CAS No. 53902-12-8
Other Names Tranilast
MFC18H17NO5
EINECS No. 53902-12-8
Purity99%min

Packaging & Delivery

Selling Units:
Kilogram

 

 

ISO Factory supply 99% purity Tranilast

 

 

 

 

 

QQ20190416134021

 

 

 

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Product Name:Tranilast
Synonyms:2-[[3-(3,4-DIMETHOXYPHENYL)-1-OXO-2-PROPENYL]AMINO] BENZOIC ACID;TRANILAST;2-((3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl)amino)-benzoicaci;n-(3,4-dimethoxycinnamoyl)-anthranilicaci;n-5’;rizaben;SB-252218;N-(3',4'-DIMETHOXYCINNAMOYL)ANTHRANILIC ACID
CAS:53902-12-8
MF:C18H17NO5
MW:327.33
EINECS: 
Product Categories:Angiotensin;Angiogenesis and Metastasis;Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;PEXID;Inhibitors
Mol File:53902-12-8.mol

 

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Items

Specification

Appearance

Light yellow or light-yellow green crystal or crystalline powder

Assay

≥98.5%

Melting point

207-210°C

Identification:

1) It appears positive reaction

2) Maximum absorbability at 333nm Wavelength                        Minimum absorbability at 263nm Wavelength

3)  Complies

Chloride

Conform

Relevant material

Conform

Loss on drying

≤0.5%

Residue on ignition

≤0.1%

Heavy metals

≤15ppm

Microbe limitation

Conform

 

 

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Tranilast is a compound that exhibits anti-inflammatory and immunomodulatory effects by inhibiting lipid mediator and cytokine release from inflammatory cells and interfering with PDGF- and TGF-β1-induced proliferation and migration of vascular medial smooth muscle cells. Tranilast suppresses production of prostaglandin D2 (IC50 = 0.1 mM), prostaglandin E2 (IC50 = ~1-20 μM), thromboxane B2 (IC50 = ~10-50 μM), TGF-β1 (IC50 = ~100-200 μM), and interleukin-8 (IC50 = ~100 μM) in in vitro models as well as attenuates of the proinflammatory activity of human monocytes. While originally marketed as an antiallergenic drug, the efficacy of tranilast in preventing restenosis after percutaneous coronary intervention has been tested in a large-scale clinical trial. Additionally, tranilast inhibits VEGF-induced angiogenetic activities (i.e., proliferation, migration and tube formation of vascular endothelial cells) with IC50 values of 22, 18 and 193 μM, which may prove therapeutic for various retinal diseases.[Cayman Chemical]

Packaging & Shipping

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Our Services

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Company Information
Qingdao Xigema Chemical Co., Ltd is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.

The aim of Xigema is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.

Xigema has become the "Top 500 Chinese manufacturing companies","Top 20 of global chemical sales".Xigema has 21 subsidiaries and holding companies.
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FAQ
Q1: Are you a manufacturer?
Answer: Yes, we are factory founded on 2002.
 
Q2: How to contact with us?
Click the Alibaba "Contact Supplier" And then send us message the product you interest in, you will get reply within 24 hours.
 
Q3:Which kind of payment terms do you accept?
For small order,you can pay by T/T,Western Union or Paypal,nomal order by T/T to our company account
 
Q4:Can you give me a discount price?
Surely,It depend on your qty
 
Q5:How can i get a sample?
free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
 
Q6: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
 
Q7:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
 

 

 

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