Manufacturer high quality Indacaterol with best price 312753-06-3

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Manufacturer high quality Indacaterol with best price 312753-06-3
Manufacturer high quality Indacaterol with best price 312753-06-3
Manufacturer high quality Indacaterol with best price 312753-06-3
Manufacturer high quality Indacaterol with best price 312753-06-3
Manufacturer high quality Indacaterol with best price 312753-06-3
Manufacturer high quality Indacaterol with best price 312753-06-3

Manufacturer high quality Indacaterol with best price 312753-06-3

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From $360.00 / Kilogram
$360.00
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If over 500pcs, mass production will start until pre-production sample has been approved.

Est. 7 days production

Product Description
 

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Specifciation:

                             1.Competitive price
                             2.Fast Delivery Within 2 days
                             3.SGS , BV, GMP,ISO approve
                             4.Professional factory

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 Name Indacaterol
 Synonyms 5-[(1R)-2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxyquinolin-2(1H)-one; QAB 149
 CAS NO. 312753-06-3

 Molecular Formula

 C24H28N2O3
 Molecular Weight 392.49
 Appearance White Solid
 Purity 99% Min
Functions

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Function

Indacaterol, a trade name of indacaterol maleate inhalation, is a chemical. Intacate is an anti-asthmatic drug (bronchodilator) and is suitable for the maintenance treatment of adult patients with chronic obstructive pulmonary disease (COPD).

 

Application

Indacaterol inhibits cAMP production in Chinese hamster ovary cells stably transfected with human β2 adrenoceptors with pEC50 of 8.06. Indacaterolinhibits electrically induced contraction on the electrically stimulated guinea pig trachea in a concentrationdependent manner with pEC50 of 8.23.Indacaterol induces a concentration-dependent inotropic effect with maximal efficacy of 75% in the isolated guinea pig left atrium [1]. Indacaterolreverses the carbachol-induced contraction in a concentration-dependent manner with IC50 of 37 nM in human small airways. Indacaterol concentration dependently reverses the serotonin-induced contraction with IC50 of 10.5 nM in rat small airways. Indacaterol has the highest intrinsic efficacy of 53% in rat small airways and 73% in human small airways [2]. Indacaterol (6.7 μg/kg) inhibits 5-HT-induced bronchoconstriction with a maximal effect of 85% in the conscious guinea pig. Indacaterol (12.5 μg/kg) dose-dependently inhibits methacholine-induced bronchoconstriction with a maximal effect of 85% in the anesthetized rhesus monkey.

Analysis

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Item

Inspection Standard

Results

Appearance 

White to off-white solid

White solid

Identification

1:NMR

Conforms

 

2:MS

 

Single impurity(max)

≤1.0%

0.56%

Heavy metals

≤0.002%

conforms

Loss on drying

≤1.0%

0.26%

Residue on ignition

≤0.5%

0.10%

Assay

≥98.0%(on dry basis, HPLC)

99.2%

 

Packaging & Shipping

 

 

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FAQ

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Q1: Are you a manufacturer?
Answer: Yes, we are factory founded on 2002.

Q2: How to contact with us?
Click the Alibaba"Contact Supplier" And then send us message the product you interest in, you will get reply within 24 hours.

Q3:Which kind of payment terms do you accept?
For small order,you can pay by T/T,Western Union or Paypal,nomal order by T/T to our company account

Q4:Can you give me a discount price?
Surely,It depend on your qty

Q5:How can i get a sample?
free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.

Q6: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

Q7:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

If you are interested,welcome to contact with us.
Pls send message if you are interested,click"send" as below ^.^

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Company Information

 

Qingdao xigema Chemical Co.,Ltd is a global chemical industry manufacturers and suppliers of pharmaceuticals 

and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.

The aim of xigema is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.

xigema has become the "Top 500 Chinese manufacturing companies","Top 20 of global chemical sales".xigema has 21 subsidiaries and holding companies.

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Our Services

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