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Manufacturer high quality docetaxel api with best price 114977-28-5
≥1 Gram
$17.50
- Item No.TOPMOQ1 Gram
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If over 500pcs, mass production will start until pre-production sample has been approved.
Est. 7 days production
Product Description
Docetaxel Anhydrous is the anhydrous form of docetaxel, a semisynthetic side-chain analogue of paclitaxel with antineoplastic property. Docetaxel binds specifically to the beta-tubulin subunit of microtubules and thereby antagonizes the disassembly of the microtubule proteins. This results in the persistence of aberrant microtubule structures and results in cell-cycle arrest and subsequent cell death.
Docetaxel was patented in 1986 and approved for medical use in 1995. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.
Certification of Analysis
Test Items | Specifications | Result | |
Appearance | White to off-white crystalline powder | Conforms | |
Characters | Practically insoluble in water, freely soluble in anhydrous ethanol, soluble in methylene chloride | Conforms | |
Specific rotation | -38.5°~41.5° | -41° | |
Identification | IR | The same to check sample | Conforms |
UV | λmax233 | Conforms | |
Colour reactions | Postive reactions | Conforms | |
HPLC | Retention times is same to the standard sample. | Conforms | |
Impurities | Impurity A:NMT 0.5% | 0.104% | |
Impurity B:NMT 0.3% | 0.017% | ||
Impurity C:NMT 0.3% | 0.012% | ||
Any other single impurity:NMT 0.1% | 0.024% | ||
Total impurities is not more than 1.0% | 0.21% | ||
Water | 5.0%~7.0% | 6.6% | |
Sulphated ash | NMT 0.1% w/w | 0.04% | |
Heavy metal | NMT 20ppm | Conforms | |
Residual solvent | Meets the requirements of ICH | Conforms | |
Bacterial endotoxins | Less than 0.3IU/mg | NMT0.3IU/mg | |
Assay | 98.5%~102.0% | 99.95% | |
Conclusion | It meets the requirements of EP7.0 | ||
Storage | Storage at 2~8°C and in a hermetical,light-resistant area. | ||
Function&Application
Docetaxel intermediate is a crucial intermediate for Docitaxel, two of the best anti-cancer drugs ever
invented. By extracting the pre-cursor, docetaxel intermediate in large quantites from the Taxus
baccata leaf, many subsequent semi-syntheses can be carried out.
The esterification of docetaxel intermediate also causes an enhancement in the kinetics, and
therefore the pharmacological profile of these important chemo-therapeutic agents.
2.Fast Delivery Within 3 days
3.SGS,BV,GMP,ISO approve
4.Professional factory
Real Photo
The aim of Xigema is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
Xigema has become the "Top 500 Chinese manufacturing companies","Top 20 of global chemical sales".Xigema has 21 subsidiaries and holding companies.
Answer: Yes, we are factory founded on 2002.
Q2: How to contact with us?
Click the Alibaba "Contact Supplier" And then send us message the product you interest in, you will get reply within 24 hours.
Q3:Which kind of payment terms do you accept?
For small order,you can pay by T/T,Western Union or Paypal,nomal order by T/T to our company account
Q4:Can you give me a discount price?
Surely,It depend on your qty
Q5:How can i get a sample?
free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
Q6: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q7:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
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