Manufacturer high quality docetaxel api with best price 114977-28-5

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Manufacturer high quality docetaxel api with best price 114977-28-5
Manufacturer high quality docetaxel api with best price 114977-28-5
Manufacturer high quality docetaxel api with best price 114977-28-5
Manufacturer high quality docetaxel api with best price 114977-28-5
Manufacturer high quality docetaxel api with best price 114977-28-5
Manufacturer high quality docetaxel api with best price 114977-28-5
Manufacturer high quality docetaxel api with best price 114977-28-5

Manufacturer high quality docetaxel api with best price 114977-28-5

  • Item No.TOP
    MOQ1 Gram
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If over 500pcs, mass production will start until pre-production sample has been approved.

Est. 7 days production

Product Description

QQ20190416134021

    Product Description

                                                

Docetaxel Anhydrous is the anhydrous form of docetaxel, a semisynthetic side-chain analogue of paclitaxel with antineoplastic property. Docetaxel binds specifically to the beta-tubulin subunit of microtubules and thereby antagonizes the disassembly of the microtubule proteins. This results in the persistence of aberrant microtubule structures and results in cell-cycle arrest and subsequent cell death.

Docetaxel was patented in 1986 and approved for medical use in 1995. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.

   Certification of Analysis

 

 

Test Items

Specifications

Result

Appearance

White to off-white crystalline powder

Conforms

Characters

Practically insoluble in water,

freely soluble in anhydrous ethanol,

soluble in methylene chloride

Conforms

Specific rotation

-38.5°~41.5°

-41°

Identification

IR

The same to check sample

Conforms

UV

λmax233

Conforms

Colour reactions

Postive reactions

Conforms

HPLC

Retention times is same to the standard sample.

Conforms

Impurities

Impurity A:NMT 0.5%

0.104%

Impurity B:NMT 0.3%

0.017%

Impurity C:NMT 0.3%

0.012%

Any other single impurity:NMT 0.1%

0.024%

Total impurities is not more than 1.0%

0.21%

Water

5.0%~7.0%

6.6%

Sulphated ash

NMT 0.1% w/w

0.04%

Heavy metal

NMT 20ppm

Conforms

Residual solvent

Meets the requirements of ICH

Conforms

Bacterial endotoxins

Less than 0.3IU/mg

NMT0.3IU/mg

Assay

98.5%~102.0%

99.95%

Conclusion

It meets the requirements of EP7.0

Storage

Storage at 2~8°C and in a hermetical,light-resistant area.

 

                          Function&Application

 

 

Docetaxel intermediate  is a crucial intermediate for Docitaxel, two of the best anti-cancer drugs ever 

invented. By extracting the pre-cursor, docetaxel intermediate  in large quantites from the Taxus

baccata leaf, many subsequent semi-syntheses can be carried out. 

 

The esterification of docetaxel intermediate also causes an enhancement in the kinetics, and 

therefore the pharmacological profile of these important chemo-therapeutic agents.

 

Our Advantages
             
 
1.Competitive price
2.Fast Delivery Within 3 days
3.SGS,BV,GMP,ISO approve
4.Professional factory

 

 

 

Real Photo

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Packaging & Shipping

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Our Services

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Company Information
Qingdao Xigema Chemical Co., Ltd is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.

The aim of Xigema is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.

Xigema has become the "Top 500 Chinese manufacturing companies","Top 20 of global chemical sales".Xigema has 21 subsidiaries and holding companies.
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FAQ
Q1: Are you a manufacturer?
Answer: Yes, we are factory founded on 2002.
 
Q2: How to contact with us?
Click the Alibaba "Contact Supplier" And then send us message the product you interest in, you will get reply within 24 hours.
 
Q3:Which kind of payment terms do you accept?
For small order,you can pay by T/T,Western Union or Paypal,nomal order by T/T to our company account
 
Q4:Can you give me a discount price?
Surely,It depend on your qty
 
Q5:How can i get a sample?
free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
 
Q6: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
 
Q7:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
 
our team

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