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Manufacturer pharma grade 99% Cabazitaxel with best price 183133-96-2
1-1000 Gram
$70.00
≥ 1001 Gram
$40.00
- Item No. TOPMOQ 1 Gram
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If over 500pcs, mass production will start until pre-production sample has been approved.
Est. 7 days production
| Cabazitaxel | CAS 183133-96-2 | Color:White |
| MW: 835.93 | MSDS: Avaiable | |
| MF :C45H57NO14 | Sample: Avaiable | |
| Category: Oncology drug | Min order: 1grams | |
| Quality standard Enterprise standard | Place of Origin:China | |
| Appearance | White powder | |
| Introduction | is a semi-synthetic derivative of a natural taxoid.It was developed by Sanofi-Aventis and was approved by the U.S. Food and Drug for the treatment of hormone-refractory prostate cancer on June 17, 2010. It is a microtubule inhibitor, and the fourth taxane to be approved as a cancer therapy. | |
| Applications | Pharmaceutical raw materials , Oncology drug | |
TEST ITEM | SPECIFICATION | |
Appearance | White or almost white crystalline powder | |
Identification | FT-IR | |
HPLC | ||
Water | 3.0% | |
Melting Point | 148°C—158°C | |
Residue on Ignition | ≤0.1% | |
Heavy metals | ≤ 20ppm | |
Residual Solvents | Acetone | ≤ 5000ppm |
Dichloromethane | ≤ 600ppm | |
n-Hexane | ≤ 290ppm | |
Acetic acid | ≤ 5000ppm | |
Ethyl acetate | ≤ 5000ppm | |
Tetrahydrofuran | ≤ 720ppm | |
Ethanol | ≤ 5000ppm | |
Related substances | cabazitaxel | ≤ 0.3% |
10-DABIII | ≤ 0.3% | |
Any other single impurity | ≤ 0.1% | |
Total impurities | ≤ 1.0% | |
Chromatographic purity(By HPLC) | ≥99.0% | |
Cabazitaxel (previously XRP-6258) is a semi-synthetic derivative of a natural taxoid. It was developed by Sanofi-Aventis and was approved by the U.S for the treatment of hormone-refractory prostate cancer on June 17, 2010. It is a microtubule inhibitor, and the fourth taxane to be approved as a cancer therapy.
Cabazitaxel in combination with prednisone is a treatment option for hormone-refractory prostate cancer following docetaxel-based treatment.
Cabazitaxel anticancer mechanism and characteristics similar with docetaxel, belongs to anti-microtubule drugs. Cabazitaxel through binding to tubulin, promoting their assembly into microtubules, and can prevent these have assembled a microtubule disintegration of the stabilization of microtubules, thereby inhibiting cell mitosis, and interphase cellular functions (interphasecellularfunctions) of play.
Answer: Yes, we are factory founded on 2002.
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Q3:Which kind of payment terms do you accept?
For small order,you can pay by T/T,Western Union or Paypal,nomal order by T/T to our company account
Q4:Can you give me a discount price?
Surely,It depend on your qty
Q5:How can i get a sample?
free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
Q6: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q7:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
Qingdao Sigma Chemical Co., Ltd.is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
The aim of Qingdao Sigma Chemical Co., Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
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