Product Name: Tianeptin Ethyl Ester Sulfate
Chemical name: 7-[(3-CHLORO-6-METHYL-5,5-DIOXIDO-6,11-DIHYDRODIBENZO[C,F][1,2]THIAZEPIN-11-YL)AMINO]HEPTANOIC ACID ETHYL ESTER SULFATE SALT

CAS No.: 66981-77-9
Assay: >98.5%

Formula: C23H29ClN2O4S  H2SO4

Introduction

Tianeptin Ethyl Ester Sulfate is an improved salt of Tianeptin. It is not hygroscopic so handling the powder is a lot easier. Since it is not as readily absorbed and excreted from the body, the sulfate salt allows for a more controlled release of the Tianeptin over longer periods. Rather than having to dose three times with rapid peak effects and rapidly falling effects, the sulfate salt allows for one dose to maintain plasma levels in the body much longer than the sodium salt. These improved characteristics make Tianeptine Sulfate a novel addition.66981-77-9

Function

Tianeptin sodium salt is a salt of Tianeptin. Tianeptin, a tricyclic compound, is a selective facilitator of 5-HT (serotonin; sc-201146) uptake in vitro and in vivo. Additionally, tianeptin sodium Tianeptine is reported to act as a selective inhibitor of dopamine uptake . Tianeptin does not have a noted effect on monoamine tianeptine sodiumuptake. In a study utilizing purified synaptosomes from rat brain, Tianeptin was reported to enhance serotonin uptake in selective brain regions. Purified synaptosomes were obtained from rats and incubated with tritium-labeled 5-HT and Tianeptin66981-77-9  in vitro . The synaptosomes were then analyzed for uptake and release of 5-HT via a liquid scintillation.

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