Pharmaceutical grade prostaglandin e1 alprostadil with best price 745-65-3



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Pharmaceutical grade prostaglandin e1 alprostadil with best price 745-65-3
Pharmaceutical grade prostaglandin e1 alprostadil with best price 745-65-3
Pharmaceutical grade prostaglandin e1 alprostadil with best price 745-65-3
Pharmaceutical grade prostaglandin e1 alprostadil with best price 745-65-3
Pharmaceutical grade prostaglandin e1 alprostadil with best price 745-65-3
Pharmaceutical grade prostaglandin e1 alprostadil with best price 745-65-3
Pharmaceutical grade prostaglandin e1 alprostadil with best price 745-65-3

Pharmaceutical grade prostaglandin e1 alprostadil with best price 745-65-3

  • Item No.TOP
    MOQ1 Gram
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From $600.00 / Gram
You save $ -600.00
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If over 500pcs, mass production will start until pre-production sample has been approved.

Est. 7 days production

Product Description

Prodcut Description



 The main component of this product is prostaglandin E1, its chemical name is (1R, 2R, 3R) -3-hydroxy-2 (E) - (3S) -3-hydroxy-1-octenyl- Alkanoic acid.

Alprostadil injection for the treatment of chronic arterial occlusion caused by limb ulcers and microvascular circulatory disorders caused by resting pain in the limbs, improve cardiovascular and cerebrovascular microcirculation disorders. Antithrombotic therapy after organ transplantation to inhibit thrombosis in transplanted blood vessels. Pediatric congenital heart disease patent ductus arteriosus, to alleviate hypoxemia, keep the catheter to wait for the timing of surgical treatment


Tests and MethodsSpecificationsResults
AppearanceWhite or slightly yellowish,crystalline powder.Conforms
(1) HPLC

The retention time of the major peak in the chromatogram 

of Assay preparation corresponds to that in the chromatogram 

of the Standard preparation, as obtained in the Assay

(2) IR absorbance Spectrum

Both the test sample and the reference standard exhibit the

 same intensity of absorption at the same wave number

(wavelengths). (potassium bromide disk method)

Optical rotation-60° to -70° (anhydrous substance). -62.56°
WaterN.M.T. 0.5%0.09%
residue on ignitionN.M.T. 0.5%0.35%
1) Related SubstancesImpurity A: N.M.T. 1.5% Not detected
Impurity B: N.M.T. 0.5% Not detected
 Any other impurity: N.M.T. 0.9% Not detected
N.M.T one Impurity more than 0.5%Conforms
Total Impurities: N.M.T. 1.5% Not detected
2) Residual solventsEthyl acetate: N.M.T. 0.5%0.22%
N-heptane:N.M.T. 0.5%0.01%
Acetone: N.M.T. 0.5%Not detected
n-Hexane: N.M.T. 0.029%Not detected
Assay95.0~102.5% ( anhydrous and solvent free basis)99.90%
Conclusion:  conforms to the requirements of EP7.0




Alprostadil injection is indicated for palliative, not definitive, therapy to temporarily maintain the patency of the ductus arteriosus until corrective or palliative surgery can be performed in neonates who have congenital heart defects and who depend upon the patent ductus for survival. Such congenital heart defects include pulmonary atresia, pulmonary stenosis, tricuspid atresia, tetralogy of Fallot, interruption of the aortic arch, coarctation of the aorta, or transposition of the great vessels with or without other defects.

In infants with restricted pulmonary blood flow, the increase in blood oxygenation is inversely proportional to pretreatment pO2 values; that is, patients with low pO2 values respond best, and patients with pO2 values of 40 torr or more usually have little response.

Alprostadil injection should be administered only by trained personnel in facilities that provide pediatric intensive care.


Packaging & Shipping

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Our Services


Company Information

Qingdao Sigma Chemical Co., a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.

The aim of Qingdao Sigma Chemical Co., Ltd is a quality policy that"Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
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Our Team

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Q1: Are you a manufacturer?
Answer: Yes, we are factory founded on 2002.
Q2: How to contact with us?
Click the Alibaba"Contact Supplier" And then send us message the product you interest in, you will get reply within 24 hours.
Q3:Which kind of payment terms do you accept?
For small order,you can pay by T/T,Western Union or Paypal,nomal order by T/T to our company account
Q4:Can you give me a discount price?
Surely,It depend on your qty
Q5:How can i get a sample?
free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
Q6: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q7:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

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