Weight Loss Pure Orlistat Powder / orlistat / CAS 96829-58-2 with best Price

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Weight Loss Pure Orlistat Powder / orlistat / CAS 96829-58-2 with best Price
Weight Loss Pure Orlistat Powder / orlistat / CAS 96829-58-2 with best Price
Weight Loss Pure Orlistat Powder / orlistat / CAS 96829-58-2 with best Price
Weight Loss Pure Orlistat Powder / orlistat / CAS 96829-58-2 with best Price

Weight Loss Pure Orlistat Powder / orlistat / CAS 96829-58-2 with best Price

  • Item No.HIgh quality
    MOQ100 Gram / Gram
  • Size 10 x 10 x 4 cm
    Weight1.2 kg
Tag  wholesale

Quantity:

From $0.550.30 / Gram
$55.00
You save $ -55.00
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If over 500pcs, mass production will start until pre-production sample has been approved.

Est. 7 days production

Quick Details
Appearance Off-White Solid
Place of Origin CN;SHN
Storage: Store at -20° C
Brand Name QDSIGEMA
alpha D20 -32.0° (c = 1 in chloroform)
Model Number HIgh quality
ApplicationWeight-Loss
solubility DMSO: 19 mg/mL
Colorwhite
storage temp. 2-8°C
Formsolid
Melting point <50 °C
Shelf time: 2 years
Merck14,6869
Type Pharmaceutical Intermediates
CAS No. 96829-58-2
Other Names Orlistat
MFC29H53NO5
EINECS No. 639-755-1
Purity99%

 

 

What is Orlistat?

Orlistat is a drug designed to treat obesity. Its primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake. It is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet.

Orlistat is the saturated derivative of lipstatin, a potent natural inhibitor of pancreatic lipases isolated from the bacterium Streptomyces toxytricini. However, due to its relative simplicity and stability, orlistat was chosen over lipstatin for development as an anti-obesity drug.

The effectiveness of orlistat in promoting weight loss is definite but modest. Pooled data from clinical trials suggest that people given orlistat in addition to lifestyle modifications, such as diet and exercise, lose about 2–3 kilograms (4.4–6.6 lb) more than those not taking the drug over the course of a year. Orlistat also modestly reduces blood pressure and appears to prevent the onset of type 2 diabetes, whether from the weight loss itself or to other effects. In a large randomized controlled trial, orlistat was found to reduce the incidence of diabetes by nearly 40% in obese people.
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Orlistat is used for the treatment of obesity.The amount of weight loss achieved with orlistat varies. In one-year clinical trials, between 35.5% and 54.8% of subjects achieved a 5% or greater decrease in body mass, although not all of this mass was necessarily fat. Between 16.4% and 24.8% achieved at least a 10% decrease in body mass.After orlistat was stopped, a significant number of subjects regained weight—up to 35% of the weight they had lost.
The incidence of type 2 diabetes in an obese population over four years is decreased with orlistat (6.2%) compared to placebo (9.0%).Long-term use of orlistat also leads to a modest reduction in blood pressure (mean reductions of 2.5 and 1.9 mmHg in systolic and diastolic blood pressure respectively).

 

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Item

Requirements

Test Results

Appearance

while   to off-while powder

White powder

Identification

HPLC   retention time

Conforms

Melting   Point

42 ºC -45°C

42°C-44°C

Specific optical   rotation

-31.0°~-41.0°

-36.0°

Purity   by HPLC

no less than 98.0%

98.5%

Total   impurity

no more than 2.0%

1.6%

Max Individual impurity

no more than 0.5%

0.3%

Water   content%(K&F)

no more than 0.5%

0.1%

Residual solvents

EtOH   no more than 0.5%

N.D

EtAC no more than 0.5%

N.D

n-Heptane no more than 0.5%

less than 0.1%

Residue on ignition

less than 0.2%

0.10%

Heavy metals as Pb

no more than 20ppm

less than20ppm

Assay   (HPLC)

no less than 98.0%

98.60%

Conclusion

Meets the Requirements

 

 

packing shipping

 

                                                       

                          

                                       25kgs packaging Fiber drum outside and plastic bag                                                

inside,1-25kgs packaging aluminium bag

outside and double plastic bag inside.

 

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Our Services

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FAQ

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Company Information

Qingdao Sigma Chemical Co., Ltd.is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.

The aim of Qingdao Sigma Chemical Co., Ltd is a quality policy that"Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
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