Top quality Capecitabine with best price 154361-50-9



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Top quality Capecitabine with best price 154361-50-9
Top quality Capecitabine with best price 154361-50-9
Top quality Capecitabine with best price 154361-50-9
Top quality Capecitabine with best price 154361-50-9
Top quality Capecitabine with best price 154361-50-9
Top quality Capecitabine with best price 154361-50-9
Top quality Capecitabine with best price 154361-50-9

Top quality Capecitabine with best price 154361-50-9

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If over 500pcs, mass production will start until pre-production sample has been approved.

Est. 7 days production

Product Description


    Product Description


Other name: Pentyl [1-(3,4-dihydroxy-5-methyl-oxolan-2-yl)-5-fluoro-2-oxo-pyrimidin-4-yl]aminoformate

CAS NO.:154361-50-9


MW: 359.35

InChI: 1S/C15H22FN3O6/c1-3-4-5-6-24-15(23)18-12-9(16)7-19(14(22)17-12)13-11(21)10(20)8(2)25-13/h7-8,10-11,13,20-21H,3-6H2,1-2H3,(H,17,18,22,23)

Melting point: 110~121℃

Appearance:white or off-white crystalline powder


Standard: EP/BP/USP

Odor: odorless

   Certification of Analysis







A white or off white crystalline powder

White crystalline powder


Freely soluble in chloroform


Specific rotation(0)[α]D20



Loss on drying(%)



Residue on ignition(%)



Heavy metals(ppm)



Metling point()

178-193 centi-degree





Related substances(HPLC)

Single impurity: ≤0.5%

Total impurity: ≤1.0%






Classification: Antineoplastic, antimetabolite Action/Kinetics: An oral prodrug of 5'-deoxy-5-fluorouridine (5'DFUR) that is converted to 5-fluorouracil (5-FU). 5-FU is metabolized to 5-fluoro-2-deoxyuridine monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP) which cause cell injury in two ways. First, FdUMP and the folate cofactor, N5-10-methylenetetrahydrofolate, bind to thymidylate synthase to form a covalently bound ternary complex which inhibits the formation of thymidylate from uracil. Thymidylate is essential for the synthesis of DNA so a deficiency inhibits cell division. Secondly, nuclear transcriptional enzymes can mistakenly incorporate FUTP in place of uridine triphosphate during RNA synthesis; this interferes with RNA processing and protein synthesis. Readily absorbed from the GI tract. Peak blood levels, capecitabine: 1.5 hr; peak blood levels, 5-FU: 2 hr. Food reduces the rate and extent of absorption. t1/2, capecitabine and 5-FU: 45 min. Metabolites excreted in the urine.


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Company Information

Qingdao Sigma chemical Co., Ltd is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
The aim of Qingdao Sigma chemical Co., Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.


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Q1: Are you a manufacturer?
Answer: Yes, we are factory founded on 2002.
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Q6: How to confirm the Product Quality before placing orders?
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Q7:How do you treat quality complaint?
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