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Top quality Clopidogrel hydrogen sulfate | 135046-48-9
1-24 Kilogram
$290.00
25 -999 Kilogram
$280.00
≥ 1000 Kilogram
$200.00
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If over 500pcs, mass production will start until pre-production sample has been approved.
Est. 7 days production
Product name: Clopidogrel hydrogen sulfate
CAS No.135046-48-9
Molecular weight: 419.03
Molecular formula: C16H16ClNO2S·H2SO4
Appearance: White crystal powder
Melting point: 174-176°C
Content: ≥ 99%
Testing Items | Specifications | Results |
Appearance | White to off-white powder | White powder |
Solubility | Freely soluble in methanol, every slightly soluble in acetone, chloroform, water and practically insoluble in anther | Complies
|
Identification | IR: As stipulated | Complies |
HPLC: As stipulated | Complies | |
It responds to the test for sulfate | Complies | |
Specific rotation | +52.0°~+56° | +54.1° |
Loss on drying | ≤0.5% | 0.19% |
Residue on igtation | ≤0.1 | 0.03% |
Related substances | Related compound A≤0.2% | 0.08% |
Related compound B≤0.3% | 0.08% | |
Any other individual impurity≤0.1% | 0.05% | |
Total impurities≤0.1% | 0.25% | |
Isomer | ≤0.1% | 0.20% |
Assay(on dry basis) | 98.5~101.5% | 99.9% |
Residual solvents | Methanol≤3000ppm | 15.4ppm |
Acetone≤5000ppm | Undetected | |
Acetonitrile≤410ppm | Undetected | |
Dichloromethane ≤600ppm | Undetected | |
Ethyl acetate≤5000ppm | 127.6ppm |
Anti-platelet aggregation drug
Thrombosis caused by arterial atheromatous plaque leads to acute thrombosis cardiovascular and cerebrovascular events. In this pathogenesis, platelets play a central role, which has been fully studied.
Clopidogrel hydrogen sulfate is similar to ticlopidine, which is a new anti-platelet aggregation drug, successfully developed by French Sanofi-Synthelabo Fort for the prevention and treatment of heart, brain and other arterial circulation disorders caused by the high blood platelet aggregation, such as recent onset of stroke, myocardial infarction and patients diagnosed with peripheral arterial disease. Many countries have already used it, including United States, Europe and China. This product inhibited platelet activation by inhibiting adenosine diphosphate (ADP) pathway to inhibit platelet aggregation. Since clopidogrel hydrogen sulfate takes several days to achieve effective blood concentration, it does not apply to emergency treatment. Stop using 7 to 10 days, platelet function returned to normal state.
Uses
Used as an antithrombotic;platelet aggregation inhibitors
Qingdao Sigma chemical Co., Ltd is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
The aim of Qingdao Sigma chemical Co., Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
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