Disulfirame is a DNA demethylating agent and DIG1 inducer which inhibits prostate cancer cell growth by inhibition of DNA methyltransferase (Dnmt). In addition, studies indicate that disulfiram inhibits aldehyde dehydrogenase (ALDH) resulting in the accumulation of acetaldehyde upon ethanol ingestion. Alternate studies show that disulfiram also inhibits dopamine β-hydroxylase (DBH), an enzyme important in converting dopamine to norepinephrine in noradrenergic neurons. Futhermore,disulfirame can reduce toxicity and carcinogenesis by inhibiting the cytochrome P450IIE1 (CYP2E1). It has been reported that disulfiram can also inhibit tumor cell growth via binding to cellular copper, which inhibits proteosome activity and induces apoptosis. Disulfiram is an inhibitor of ADH and V-ATPase.
white with yellowness greenish hue,to light
yellow with greenish hue color crystalline powder
Color of solution
D under 440ml<0.2
Loss of Drying
This product conforms toUSP28
Light yellow or grey white crystal (Granule). The density is 1.29. Soluble in benzene, acetone, chloroform, CS2 partly soluble in alcohol, diethyl ether, CCl4 insoluble in water, gasoline and alkali with lower concentration. Meeting hot water becomes to dimethyl ammonium and CS2. Be sensitive to skin and good storage stability.
Fast-curing primary or secondary accelerator for NR, SBR, Nitrile and EPDM. Closely resembles TMTD in its applications. Less scorch, blooming and good processing safety. Can be used in CR as an anti-scorching agent. The efficiency sulphur content is 11 %. It is also be used as raw material for germicide, pesticide and medicine
Qingdao Sigma chemical Co., Ltd is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc. The aim of Qingdao Sigma chemical Co., Ltd is a quality policy that"Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
Packaging & Shipping
Q1: Are you a manufacturer? Answer: Yes, we are factory founded on 2002.
Q2: How to contact with us? Click the Alibaba"Contact Supplier" And then send us message the product you interest in, you will get reply within 24 hours.
Q3:Which kind of payment terms do you accept? For small order,you can pay by T/T,Western Union or Paypal,nomal order by T/T to our company account
Q4:Can you give me a discount price? Surely,It depend on your qty
Q5:How can i get a sample? free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
Q6: How to confirm the Product Quality before placing orders? A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q7:How do you treat quality complaint? A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.