Flubendazole is a synthetic anthelmintic belonging to the benzimidazole carbamates which acts by inhibiting the microtubular assembly in absorptive cells of nematodes.
Flubendazole acts by binding to tubulin, the dimeric subunit protein of the microtubules.
Flubendazole inhibits microtubular assembly in absorptive cells: i.e. of intestinal cells of nematodes.
This is shown by disappearance of cytoplasmic microtubules,accumulation of secretory granules in the cytoplasm due to a block in their transport, leading to an impaired coating of the cellular membrane and a decreased digestion and absorption of nutrients. Irreversible lytic degeneration of the cell,due to the accumulation of secretory substances (hydrolytic and proteolytic enzymes), results in the death of the parasite.
Flubendazole is a broad-spectrum anthelminthic agent effective against endoparasites such as gastro-intestinal ascarids, hookworms, whipworms found in dogs,and active a range of gastrointestinal parasites in pigs and poultry such as roundworms,and tapeworms,Ascaris suum (large roundworm), gapeworms, Hyostrongylus rubidus (red stomach worm),Oesophagostomum dentatum (nodular worm),Trichuris suis (whip worm), Strongyloides ransomi (adult),Metastrongylus apri (lungworm).Flubendazole is ovicidal.
Certification of Analysis
White or almost white powders
Almost white powders
Complies with spectrum of flubendazol CRS
Any other impurity with a relative retention between 1.2 and 1.3
Any Other Impurity
Loss on Drying
99.0%~101.0% calculated on the dry basis
Assay of Polymorphic b (IR)
CONCLUSION :The items tested meet the requirement of EUROPEAN PHARMACOPOEIA 7.0
Flubendazole is a synthetic benzimidazole de-worming drugs,can inhibit the absorption of cells of the worm microtubule polymerization.
Flubendazole is a broad-spectrum anthelmintic,effective in treatment of dogs in vivo parasites,such as gastrointestinal roundworm,hookworm,whipworm;but also pigs and poultry,the body can be treated in many gastrointestinal parasites,such as large Pig roundworm (Ascaris suum),stomach red pig round worm (Hyostrongylus rubidus),there are Oesophagostomum (Oesophagostomum dentatum),pig whipworm (Trichuris suis),lung,after a round worm (Metastrongylus apri) and so on.
Flubendazole can not only kill the adult, it can also kill eggs.
Qingdao Sigma chemical Co., Ltd is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc. The aim of Qingdao Sigma chemical Co., Ltd is a quality policy that"Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
Packaging & Shipping
Q1: Are you a manufacturer? Answer: Yes, we are factory founded on 2002. Q2: How to contact with us? Click the Alibaba "Contact Supplier" And then send us message the product you interest in, you will get reply within 24 hours. Q3:Which kind of payment terms do you accept? For small order,you can pay by T/T,Western Union or Paypal,nomal order by T/T to our company account Q4:Can you give me a discount price? Surely,It depend on your qty Q5:How can i get a sample? free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future. Q6: How to confirm the Product Quality before placing orders? A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests. Q7:How do you treat quality complaint? A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.