Top quality Polyvinylpyrrolidone cross-linked/PVPP with best price 25249-54-1

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Top quality Polyvinylpyrrolidone cross-linked/PVPP with best price 25249-54-1
Top quality Polyvinylpyrrolidone cross-linked/PVPP with best price 25249-54-1
Top quality Polyvinylpyrrolidone cross-linked/PVPP with best price 25249-54-1
Top quality Polyvinylpyrrolidone cross-linked/PVPP with best price 25249-54-1
Top quality Polyvinylpyrrolidone cross-linked/PVPP with best price 25249-54-1
Top quality Polyvinylpyrrolidone cross-linked/PVPP with best price 25249-54-1
Top quality Polyvinylpyrrolidone cross-linked/PVPP with best price 25249-54-1

Top quality Polyvinylpyrrolidone cross-linked/PVPP with best price 25249-54-1

  • Item No.TOP
    MOQ1 Kilogram
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If over 500pcs, mass production will start until pre-production sample has been approved.

Est. 7 days production

Quick Details
Product name Polyvinylpyrrolidone cross-linked
MW111.14176
Place of Origin CN;SHN
Usage Animal Pharmaceuticals
Brand Name QDXIGEMA
Model Number TOP
Color White to off-white
Water Solubility Insoluble in water, acid and alkaline.
Formpowder
Melting point ~165 °C (dec.)(lit.)
Shelf Life 2 Years
Grade Standard Medicine Grade
Type Auxiliaries and Other Medicinal Chemicals
CAS No. 25249-54-1
Other Names PVPP
MFC6H9NO
EINECS No. 201-800-4
Purity99%

Packaging & Delivery

Selling Units:
Kilogram
Product Description

 Product Profile

                                               

Cross Povidone is often called as crosslinked PVP, or insoluble PVP. It appears as white or light yellow, free flowing hygroscopic powder, odorless or with faint characteristic odor. It is insoluble in water, alkali, acid and common organic

solvents. It has strong swellability and can complex with polyphenols, carboxylic acid and other compounds with low

molecular weight.

 

 Test Report

 

 

Items

Specification

Apperaence

Hygroscopic,white or yellowish-white powder

Solubility

Practically insoluble in water,in ethanol 96% and in methylene chloride

Indetification

A.IR

B.No blue color develops within 30s

C.A suspension is formed,and no clear solution is obtained within 15 min

D.15% max(sieving redisue fraction)

Peroxide (as H2O2)

1000ppm max

Water-soluble substances

1.5% max

Impurity A(NVP)

10ppm max

Loss on drying

5.0% max

Heavy metals

10ppm max

Sulfated ash

0.1% max

Content(Nitrogen)

11.0%-12.8%

TAMC

1000cfu/g

TYMC

100cfu/g

Staphylococcus aureus

Negative in 1g

Salmonella

Negative in 10g

Pseudomonas aeruginosa

Negative in 1g

E.Coli

Negative in 1g

Conclusion:

Meet the requirement of EP standard.

 

                    Function

 

 

Function:

     This article used as a tablet, granules, pill disintegrating agent and filling agent,Because crosslinking povidone high molecular weight and crosslinking, insoluble in water but in water is bringing water quickly, and urges the network structure expansion crumbling effect, still is widely used in and tablets to excipients.

1. Used as stabilizer for beer,wine,vinegar and many juice and beverage to prolong their storage life.

2. Used as disintegrant for tabel pill,parrical-like granule and capsule drug in Harmaceutical industry.

3. Pharmaceutical Industry : Provide rapid disintegration in a wide range of oral solid dosage formulations and processes. Especially in the following areas:

4.In wet granulation tablet processes.

5.Ideally suited for use with poorly compressible drug actives and in direct compression tablet processes.

6.Outstanding performance in manufacturing ionic, acidic and alkaline drug actives 
7.Quick dissolve and chewable tablets .

8.Treat gastrointestinal disorders and as an anti-diarrhea agent

Application:

     It can be widely used in pharmaceutical, food, personal care, feed field, etc. In the biological pharmaceutical field PVPP has good physiologic inertia and biological compatibility characteristics. It can be used as disintegration agent, medicine slow-releasing carrier and hemodialysis film, etc. After PVPP absorb water and it makes tablet(capsule) bear very high pressure, then disintegrate small incalculable grain, it improved biological availability of body.

 

To assure the effectiveness of the medicine,tablets and capsules are required to disintegrate within a certain time,if different adding methods of the disintegrating agent are used,the different disintegrating and dissolution speeds witll be achieved.PolyKoVidone is regarded as the top disintegrating agent thanks to its excellent swelling characteristics after the absoption of moisture.

 

Highly efficient disintegrating agent:Makes all excipients swell quickly,effective for wet & dry granulations and direct compression formulations,PolyKoVidone can be added before or after granulation.Its swelling action and disintegration time will be not impacted by wetting or drying.

Suspension stabilizer:PolyKoVidone acts as a hydrophilic polymer,increasing the viscosity , improving the dispersal capacity,reducing the sedimentation rate of drugs,meanwhile,increasing the redispersal capacity of the solution sediment,suitable for liquid preparations and instant oral preparations.

 

Complextant of drug ingredients:Stablizing the active ingredients in pharmaceutical products,improving the dissolution and bioavailability.

 

Complextant of Tannin and Polyphenols:In the aqueous or alcoholic herbal extracts,Polyphenols are absorbed selectively by PolyKoVidone and complexed,and finally filtered off.

 

Packaging & Shipping

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Our Services

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Company Information

Qingdao Sigma chemical Co., Ltd is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
 
The aim of Qingdao Sigma chemical Co., Ltd is a quality policy that"Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.

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FAQ
Q1: Are you a manufacturer?
Answer: Yes, we are factory founded on 2002.
 
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Q6: How to confirm the Product Quality before placing orders?
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Q7:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
 
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