Top quality Polyvinylpyrrolidone cross-linked/PVPP with best price 25249-54-1
≥1 Kilogram
$11.00
- Item No. TOPMOQ 1 Kilogram
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If over 500pcs, mass production will start until pre-production sample has been approved.
Est. 7 days production
Cross Povidone is often called as crosslinked PVP, or insoluble PVP. It appears as white or light yellow, free flowing hygroscopic powder, odorless or with faint characteristic odor. It is insoluble in water, alkali, acid and common organic
solvents. It has strong swellability and can complex with polyphenols, carboxylic acid and other compounds with low
molecular weight.
Items | Specification | ||
Apperaence | Hygroscopic,white or yellowish-white powder | ||
Solubility | Practically insoluble in water,in ethanol 96% and in methylene chloride | ||
Indetification | A.IR | ||
B.No blue color develops within 30s | |||
C.A suspension is formed,and no clear solution is obtained within 15 min | |||
D.15% max(sieving redisue fraction) | |||
Peroxide (as H2O2) | 1000ppm max | ||
Water-soluble substances | 1.5% max | ||
Impurity A(NVP) | 10ppm max | ||
Loss on drying | 5.0% max | ||
Heavy metals | 10ppm max | ||
Sulfated ash | 0.1% max | ||
Content(Nitrogen) | 11.0%-12.8% | ||
TAMC | 1000cfu/g | ||
TYMC | 100cfu/g | ||
Staphylococcus aureus | Negative in 1g | ||
Salmonella | Negative in 10g | ||
Pseudomonas aeruginosa | Negative in 1g | ||
E.Coli | Negative in 1g | ||
Conclusion: | Meet the requirement of EP standard. |
Function:
This article used as a tablet, granules, pill disintegrating agent and filling agent,Because crosslinking povidone high molecular weight and crosslinking, insoluble in water but in water is bringing water quickly, and urges the network structure expansion crumbling effect, still is widely used in and tablets to excipients.
1. Used as stabilizer for beer,wine,vinegar and many juice and beverage to prolong their storage life.
2. Used as disintegrant for tabel pill,parrical-like granule and capsule drug in Harmaceutical industry.
3. Pharmaceutical Industry : Provide rapid disintegration in a wide range of oral solid dosage formulations and processes. Especially in the following areas:
4.In wet granulation tablet processes.
5.Ideally suited for use with poorly compressible drug actives and in direct compression tablet processes.
6.Outstanding performance in manufacturing ionic, acidic and alkaline drug actives
7.Quick dissolve and chewable tablets .
8.Treat gastrointestinal disorders and as an anti-diarrhea agent
Application:
It can be widely used in pharmaceutical, food, personal care, feed field, etc. In the biological pharmaceutical field PVPP has good physiologic inertia and biological compatibility characteristics. It can be used as disintegration agent, medicine slow-releasing carrier and hemodialysis film, etc. After PVPP absorb water and it makes tablet(capsule) bear very high pressure, then disintegrate small incalculable grain, it improved biological availability of body.
To assure the effectiveness of the medicine,tablets and capsules are required to disintegrate within a certain time,if different adding methods of the disintegrating agent are used,the different disintegrating and dissolution speeds witll be achieved.PolyKoVidone is regarded as the top disintegrating agent thanks to its excellent swelling characteristics after the absoption of moisture.
Highly efficient disintegrating agent:Makes all excipients swell quickly,effective for wet & dry granulations and direct compression formulations,PolyKoVidone can be added before or after granulation.Its swelling action and disintegration time will be not impacted by wetting or drying.
Suspension stabilizer:PolyKoVidone acts as a hydrophilic polymer,increasing the viscosity , improving the dispersal capacity,reducing the sedimentation rate of drugs,meanwhile,increasing the redispersal capacity of the solution sediment,suitable for liquid preparations and instant oral preparations.
Complextant of drug ingredients:Stablizing the active ingredients in pharmaceutical products,improving the dissolution and bioavailability.
Complextant of Tannin and Polyphenols:In the aqueous or alcoholic herbal extracts,Polyphenols are absorbed selectively by PolyKoVidone and complexed,and finally filtered off.
Qingdao Sigma chemical Co., Ltd is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
The aim of Qingdao Sigma chemical Co., Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
Answer: Yes, we are factory founded on 2002.
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Q3:Which kind of payment terms do you accept?
For small order,you can pay by T/T,Western Union or Paypal,nomal order by T/T to our company account
Q4:Can you give me a discount price?
Surely,It depend on your qty
Q5:How can i get a sample?
free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
Q6: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q7:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
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