Top quality Ranitidine Hydrochloride with best price 66357-59-3



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Top quality Ranitidine Hydrochloride with best price 66357-59-3
Top quality Ranitidine Hydrochloride with best price 66357-59-3
Top quality Ranitidine Hydrochloride with best price 66357-59-3
Top quality Ranitidine Hydrochloride with best price 66357-59-3
Top quality Ranitidine Hydrochloride with best price 66357-59-3
Top quality Ranitidine Hydrochloride with best price 66357-59-3
Top quality Ranitidine Hydrochloride with best price 66357-59-3

Top quality Ranitidine Hydrochloride with best price 66357-59-3

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Quick Details
Product name Ranitidine Hydrochloride
Place of Origin CN;SHN
Usage Animal Pharmaceuticals
storage temp Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Model Number top
solubility H2O: 1.8 mg/mL
Color White Color
Melting point 134°C (dec.)
Shelf Life 2 years
Grade Standard Medicine Grade
Type Auxiliaries and Other Medicinal Chemicals
CAS No. 66357-59-3
Other Names Ranitidine Hydrochloride
EINECS No. 266-332-5

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Product Description

Basic Information

Molecule: C13H22N4O3S·HCL
Molecule Weight: 350.87
CAS NO.: 66357-59-3
HS CODE: 29321900
Quality Standard: CP2010, USP29
Ranitidine is a histamine H2 receptor antagonist that inhibits stomach acid production. It is commonly used in treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD). Ranitidine is also used alongside fexoamines for the treatment of skin conditions such as hives.


Test Report





Positive reaction



Loss on drying

Not more than 0.75%

Residue on ignition

Not more than 0.1%

Chromatographic purity

Ranitidine Related Compound B not more than 0.5%

Any other impurity not more than 0.3%

The sum of all impurities not more than 1.0%

Organic volatile impurities

Meets the requirements

Residual solvents

Meets the requirements

Assay(dry substance)




1.For the treatment of active peptic ulcer and diseases of high gastric acid secretion. Intravenous injection of this product can reduce gastric acid secretion by 90% that can be used during acute stress gastric mucosal damage, and aspirin-induced acute gastric mucosal injury. On the Zollinger-Ellison syndrome, a large number of ranitidine may inhibit gastric acid secretion, symptoms. Also used for general anesthesia or coma patients after major surgery and weakness to prevent acid reflux with inhalation pneumonia.
2.Suitable for postoperative gastric ulcer, duodenal ulcer, ulcer, reflux esophagitis, etc.
3.Clinical findings and ranitidine in the Treatment of Recurrent Aphthous ulcer and other diseases also have good effect.


Application Area
1.Recurrent oral ulcer
Use of ranitidine in the treatment of recurrent aphthous ulcer, pain within 1-2 days 3-5 days to heal, the total effective rate of 100%, and metronidazole in the treatment of control group is 85%, there are significant differences. Usage: oral ranitidine 150 mg per time, 2 times per day, or ranitidine Ding Yan into fine powder and apply directly on the ulcer surface, 3 times per day until the symptoms disappear.

Application of ranitidine in treatment of patients with mumps, the effect is significant, significantly better than the control group treated with Morpholine croak. Usage: oral ranitidine, 15 mg/kg ·, 2 suits, for 3 days in a row. If the heat is too high, and with physical cooling.

3.Ulcerative colitis
Ranitidine was used to treat patients with ulcerative colitis, the total effective rate of 95%. Usage: oral ranitidine 150 mg per time, daily morning and evening 1, taken in March.

4.Verrucous gastritis
Application of ranitidine in the treatment of Verrucous gastritis and achieve significant efficacy in one week, the total effective rate of 87%, while the control group only 33%, very significant differences between the two groups. Usage: oral ranitidine 150 mg per time, morning and evening, 1 times, warm water delivery service, for 1 course of

5 weeks.

5.Eosinophilic Fasciitis
Application of ranitidine in treatment patients with Eosinophilic Fasciitis, with good results. General Medicine 1 month can be effective six months after the partial recovery of skin lesions. Usage: oral ranitidine 150 mg per time, early, middle and late each take 1 times, warm water delivery service.

6.Non-ulcer dyspepsia
Oral administration of ranitidine hydrochloride for the treatment of patients with non-ulcer dyspepsia, the effect is significant, remission rate of 76%, the treatment group than the control group. Usage: oral ranitidine 150 mg per time, 2 times per day for 6 weeks.

7.Chronic diarrhea
The disease may lead to increased intestinal mast cells, have been stimulated to release histamine, causing local congestion, edema, muscle cramps and diarrhea occurs. Ranitidine works by inhibiting histamine release and to good effect. Most patients stool within 1 week, less often, and get the healing effect. Usage: oral ranitidine 150 mg per time, early, middle, late 1 times, warm water delivery service.

8.Herpes Simplex
Use of ranitidine in the treatment of Herpes Simplex, typically coated with 3~5 pain away, early cases without a blister, blister blister dries up, scabs in 2 days. Ranitidine was also used in the treatment of 29 cases of herpes simplex are cured within 2-4 days. And no scar after healing occurs. Usage: take ranitidine capsules (150 mg), 1 capsule, the powder dissolved in water, made of exterior coating solution on the affected area, dressing 1 1-2 hours.

Application of ranitidine in the treatment of urticaria, is satisfactory with medication after 1 treatment efficiency of 80%, the total effective rate of 90%. Methods: 5% ranitidine Ding Shuang agent, application of Yu Shenjue, wind pool, Xuehai, each point 50 mg, covers 3.5~6 square tape wound 1 time every 3 days, 2 times for 1 course, continuous treatment until symptoms disappear.

10.Von Willebrand disease
Application of ranitidine in the treatment of hemophilia, can increase plasma levels of factor VIII or factor IX, clinical symptoms improved, after 12 hours to stop bleeding. Usage: oral ranitidine 150 mg per time, morning and evening, 1. Pediatric dosage by age descending, for 15 days. Another continuous maintenance treatment with ranitidine, were also better efficiency. 

Company Information

Qingdao Sigma chemical Co., Ltd is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
The aim of Qingdao Sigma chemical Co., Ltd is a quality policy that"Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.


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