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Top quality Rosuvastatin calcium with best price 147098-20-2
≥1 Kilogram
$1,416.66
- Item No.topMOQ1 Kilogram
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If over 500pcs, mass production will start until pre-production sample has been approved.
Est. 7 days production
Product Description
| Name | Rosuvastatin calcium |
| Synonyms | 7-{4-(4-Fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid |
| Molecular Formula | 2(C22H27FN3O6S).Ca;C44H54CaF2N6O12S2 |
| Molecular Weight | 1001.14 |
| CAS Registry Number | 147098-20-2 |
| Melting point | 122 ºC |
Rosuvastatin Calcium is the calcium salt form of rosuvastatin, a statin with antilipidemic activity. Rosuvastatin selectively and competitively binds to and inhibits hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate, a precursor of cholesterol. This leads to a decrease in hepatic cholesterol levels and increase in uptake of LDL cholesterol.
Certification of Analysis
Tests | Specifications | Results |
Appearance | A White to off-white powder | Complies |
Specific Rotation | +17°~+21° | +20° |
Identification | A. Meets the requirement B. UV: λmax=243nm C. IR: similar to Reference Substance D.X-ray: similar to Reference Substance | Complies Complies Complies Complies |
Chloride | ≤0.1% | Complies |
Sulphate | ≤0.1% | Complies |
Enantiomer | ≤0.15% | Undetected |
Calcium | 3.9%~4.3% | 4.1% |
Related substances | Diastereomer≤0.15% | 0.06% |
5-oxo-Rosucastatin≤0.15% | Undetected | |
Photo degradation 1≤0.15% | Undetected | |
Photo degradation 2≤0.15% | Undetected | |
Rosuvastatin lactone≤0.15% | Undetected | |
Rosuvastatin methyl ester≤0.15% | Undetected | |
Rosuvastatin isoamyl ester≤0.15% | Undetected | |
Any unknown impurity≤0.10% | 0.05% | |
Total impurities≤0.75% | 0.28% | |
Water | ≤3.0% | 2.1% |
Isoamyl Bromide | ≤37.5ppm | ≤37.5ppm |
Residual solvents | Ethyl ether≤300ppm Undetected | Complies |
Acetonitrile≤410ppm Undetected | Undetected | |
Isoamyl alcohol≤5000ppm Undetected | Undetected | |
DMF≤880ppm Undetected | Undetected | |
Assay | 98.5%~102.0%( caculated on the anhydrous basis) | 99.8% |
Function&Application
Rosuvastatin calcium is a HYDROXYMETHYLGLUTARYL-COA-REDUCTASE INHIBITOR, or statin, that reduces the plasma concentrations of LDL-CHOLESTEROL; APOLIPOPROTEIN B, and TRIGLYCERIDES while increasing HDL-CHOLESTEROL levels in patients with HYPERCHOLESTEROLEMIA and those at risk for CARDIOVASCULAR DISEASES.
Answer: Yes, we are factory founded on 2002.
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Q3:Which kind of payment terms do you accept?
For small order,you can pay by T/T,Western Union or Paypal,nomal order by T/T to our company account
Q4:Can you give me a discount price?
Surely,It depend on your qty
Q5:How can i get a sample?
free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
Q6: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q7:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
Qingdao Sigma chemical Co., Ltd is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
The aim of Qingdao Sigma chemical Co., Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
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