High quality CAS 1224690-84-9 Tianeptine sulfate
Other name: Tianeptine hemisulfate monohydrate
CAS No.: 1224690-84-9
Mol. Formula: C21H27ClN2O8S2
Appearance : white powder,very hygroscopic.
Assay HPLC: (on anhydrous basis): 99%
Melting point : 176-178℃
Loss on drying ≤5.0% 1.38%
Shelf life : keep away from strong light and heat 2 years when properly stored
Storage: Store cool and dry, recommended storage temperature 2-10℃
Tianeptine is a drug used primarily in the treatment of major depressive disorder, although it may also be used to treat asthma or irritable bowel syndrome. Chemically it is a tricyclic antidepressant (TCA), but it has different pharmacological properties than typical TCAs as recent research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (i.e., AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.
Tianeptinehas antidepressant and anxiolytic (anti-anxiety) properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in the elderly and in those following alcohol withdrawal; such persons can be more sensitive to the adverse effects of psychotropic drugs. Recent results indicate possible anticonvulsant (anti-seizure) and analgesic (painkilling) activity of tianeptine via immediate or downstream modulation of adenosine A1 receptors (as the effects could be experimentally blocked by antagonists of this receptor).
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