USA Warehouse provide Tianeptin sodium,Tianeptin AcidandTianeptin Sulfate

Tianeptin sodium salt  is a salt of Tianeptin. Tianeptin, a tricyclic compound, is a selective facilitator of 5-HT (serotonin; sc-201146) uptake in vitro and in vivo. Additionally, Tianeptin is reported to act as a selective inhibitor of dopamine uptake . Tianeptin does not have a noted effect on monoamine uptake. In a study utilizing purified synaptosomes from rat brain, Tianeptin was reported to enhance serotonin uptake in selective brain regions. Purified synaptosomes were obtained from rats and incubated with tritium-labeled 5-HT and Tianeptin in vitro . The synaptosomes were then analyzed for uptake and release of 5-HT via a liquid scintillation.

Tianeptin  has antidepressant and anxiolytic (anti-anxiety) properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in the elderly and in those following alcohol withdrawal; such persons can be more sensitive to the adverse effects of psychotropic drugs. Recent results indicate possible anticonvulsant (anti-seizure) and analgesic (painkilling) activity of tianeptin via immediate or downstream modulation of adenosine A1 receptors (as the effects could be experimentally blocked by antagonists of this receptor).

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