1-1000 Kilograms
$220.00
≥1001 Kilograms
$180.00
Product Description
Cyclophosphamide is a drug that has no antitumor activity in vitro and enters the body first in liver microorganism function oxidase. And amides are unstable, forming amidomustard and acrolein in tumor cells, which have cytotoxic effects on tumor cells. Cyclophosphamide is a bifunctional alkylation agent and cell cycle nonspecific drug, which can interfere with the function of DNA and RNA, especially in the former, which has a great influence. Cyclophosphamide crosslinks with DNA and inhibits DNA synthesis.
Certification of Analysis
TEST | SPECIFICATION | RESULT |
Description | White crystaline powder | Conforms |
Identification A | IR, UV conform | Conforms |
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Identification B | Should conform | Conforms |
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PH Value | Between 3.9 to 7.1 | 5.3 |
Water | Between 5.7%~6.8% | 6.5 |
Heavy metals | Not more than 0.002% | <0.001% |
Chlorides | Not more than 0.018% | 0.001% |
Melting range | Between 48.5°C and 52°C | 49.2°C ~50.4°C |
Bacterial endotoxin | Not more than 0.2 | Conforms |
Sterility test | Meet the requirements | Conforms |
Limit of Propanolamine | ≤0.025% | Conforms |
Limit of Phosphate | ≤0.01% | Conforms |
Residual solvents | Alcohol: not more than 0.5% | 100ppm |
| Acetone: not more than 0.5% | 80ppm |
Assay | Between 97.0 and 103.0% | 99.2% |
CONCLUSION:Conform to USP |
Function&Application
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
The product is the most commonly used alkylating agent antineoplastic drugs, into the body, the liver microsomal enzyme decomposition of the decomposition of the release of a strong alkylation of chloroethyl phosphate (or phosphoramide nitrogen mustard), and Tumor cells produce cytotoxic effect, in addition to this product also has significant immunosuppressive effect.
Clinical for malignant lymphoma, multiple myeloma, leukemia, breast cancer, ovarian cancer, cervical cancer, prostate cancer, colon cancer, bronchial cancer, lung cancer, have a certain effect. Can also be used for rheumatoid arthritis, nephrotic syndrome in children and the treatment of autoimmune diseases.
Qingdao Sigma chemical Co., Ltd is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
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