1-1000 Kilograms
$320.00
≥1001 Kilograms
$250.00
Product Description
Product name | Pyridostigmine bromide |
CAS NO. | 101-26-8 |
Synonyms | Pyridostigmine bromide |
Category | Pharmaceutical Raw Materials,Active Pharmaceutical Ingredients,Bulk Drugs,Fine Chemicals. |
Standard | purity:>99% |
Appearance | Pyridostigmine bromide powder |
Shelf life | 2 years |
Usage | Pyridostigmine bromide is used to treat muscle weakness in people with myasthenia gravis and to combat the effects of curariform drug toxicity. |
Storage | Pyridostigmine bromide should be stored in a well-closed container at low temperature, keep away from moisture, heat and light. |
Certification of Analysis
Item | Specification |
Specific rotation | +39.5 to +41.5° |
State of solution(transmittance) | Clear 98.0% min. |
Chloride[cl] | 0.020% max. |
Ammonium [NH4] | 0.02% max. |
Sulfate[SO4] | 0.020% max |
Iron[Fe] | 10ppm max. |
Heavy metals [Pb] | 10ppm max |
Arsenic[As2O3] | 1ppm max |
Other amino acids | Chromatographically not detectable |
Loss on drying | 0.20% max. |
Residue on ignition[sulfated] | 0.10% max. |
Assay | 99.0% min |
Function&Application
1. It can inhibit the activity of cholinesterase in plasma, make the local anesthetics of ester group hydrolyze slowly in vivo, and easy to cause toxic reaction.Therefore, it is advisable to use an amide local anesthetic during the use of this drug.
2. Aminoglycoside antibiotics, capreomycin, lincomycin, polymyxin, lidocaine intravenous injection or quinine intramuscular injection can all act on neuromuscular joint and weaken skeletal muscle tone. Therefore, different degrees of antagonism can be generated in the action of this drug.
3. Can weaken the muscle relaxation effect of ether, enflurane, isoflurane, methoxyflurane, cyclopropane and other inhaled anesthetics.
4. The antihypertensive drugs (such as guanidine, megammine and mifen) that block sympathetic ganglion can weaken the effect of this drug.
5. Even weak anti-muscarinoid drugs (such as procaine and quinidine, etc.) can weaken the effect of this drug on myasthenia gravis, so it is not suitable for use.
6. Atropine ACTS on m-cholinergic receptor, which can reduce the adverse reactions of the cholinesterase inhibitory drug overdose. Therefore, when this drug is used to antagonize non-depolarizing muscle relaxants, it can be used together with atropine.
Qingdao Sigma chemical Co., Ltd is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
The aim of Qingdao Sigma chemical Co., Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
Scan the QR code with your phone, or visit the URL