1-1000 Grams
$10.00
≥1001 Grams
$2.00
Product Description
product Name | 53251-94-8 |
---|---|
Synonyms | N-ethyl-N-(4-pyridylmethyl)tropamide; N-Ethyl-3-hydroxy-2-phenyl-N-(pyridin-4-ylmethyl)propanamideBenzeneacetamide, N-ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)- bistropamide; component of Paremyd; epitromina; Mydriacyl; mydriat; mydrin; mydrum; n-ethyl-2-phenyl-n-(4-pyridylmethyl)-hydracrylamid; N-Ethyl-3-hydroxy-2-phenyl-N-(4-pyridinylmethyl)propanamide; n-ethyl-alpha-(hydroxymethyl)-n-(4-pyridinylmethyl)-benzeneacetamid; ro1-7683; visumidriatic; n-ethyl-3-hydroxy-2-phenyl-n-(pyridin-4-ylmethyl)propanamide; N-ETHYL-3-HYDROXY-2-PHENYL-N-PYRIDIN-4-YLMETHYL-PROPIONAMIDE; N-ETHYL-3-HYDROXY-2-PHENYL-N-(PYRIDINYLMETHYL)PROPANAMIDE; 3-[[(4,5-dihydro-1 H -imidazol-2-yl)methyl](4-methylphenyl)amino]-,monomethanesulfonate (salt); (2R)-N-ethyl-3-hydroxy-2-phenyl-N-(pyridin-4-ylmethyl)propanamide; (2S)-N-ethyl-3-hydroxy-2-phenyl-N-(pyridin-4-ylmethyl)propanamide |
Molecular Formula | C17H20N2O2 |
Molecular Weight | 284.3529 |
InChI | InChI=1/C17H20N2O2/c1-2-19(12-14-8-10-18-11-9-14)17(21)16(13-20)15-6-4-3-5-7-15/h3-11,16,20H,2,12-13H2,1H3/t16-/m1/s1 |
CAS Registry Number | 1508-75-4 |
EINECS | 216-140-2 |
Density | 1.161g/cm3 |
Boiling point | 492.8°C at 760 mmHg |
Refractive index | 1.586 |
Flash point | 251.8°C |
Vapour Pressur | 1.58E-10mmHg at 25°C |
Certification of Analysis
Items | Specifications | Results |
Appearance | White crystalline powder | Conforms |
Melting point | 157°C~163°C | 157.9°C~160.8°C |
Specific rotation | -6.5°~-8.5° | -7.6° |
Identification | UV: Maximun absorption at 246nm and 288nm IR: The sample gives the same IR spectrum with the standard spectrum of pinaverium bromide Chemical reation: it responds to the test for bromine in water | Conforms Conforms
Conforms |
Crystallinity | Conforms | Conforms |
Bromine | 13.3%~13.9% | 13.43% |
PH | 5.0~7.0 | 5.67 |
Clarity and color | Conform | Conforms |
Trans isomer, GC | ≤3.0% | 0.64% |
Other volatile substance, GC | Individual impurity ≤0.2% Total impurities≤ 0.5% | 0.10% 0.24% |
Related compounds HPLC | Individual impurity ≤0.2% Total impurities ≤0.5% | 0.08% 0.20% |
Residual solvents, GC | Dichloromethane ≤200ppm Methyl ethyl Ketone ≤1000ppm Toluene≤ 440ppm Methanol ≤1000ppm N-Hexane ≤250ppm Ethanol ≤1000ppm | ND 84.0ppm ND ND ND ND |
Loss on drying | ≤0.5% | 0.10% |
Residue on ignition | ≤0.1% | 0.05% |
Heavy metals | ≤0.002% | 0.002% |
Assay (anhydrous basis), potentiometric titratoin | ≥99.0% | 99.8% |
Conclusion: this batch conforms as per above specifications. |
Function&Application
Pinaverium bromide is suitable for irritable bowel syndrome, symptomatic treatment pain associated with bowel dysfunction Abnormal bowel movements and discomfort, colon spasms, symptomatic treatment pain associated with biliary disorders, peptic ulcer, gallbladder movement disorders, in preparation for a barium enema.
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