1-1000 Grams
$100.00
≥1001 Grams
$10.00
Product Description
Name | Methotrexate |
Synonyms | (+)-Amethopterin; (+)-4-Amino-10-methylfolic acid; N-(p-(((2,4-Diamino-6-pteridinyl)methyl)methylamino)benzoyl)-L-glutamic acid |
Molecular Formula | C20H22N8O5 |
Molecular Weight | 454.44 |
CAS Registry Number | 59-05-2 |
EINECS | 200-413-8 |
Certification of Analysis
Test Item | Analysis Specification | Result |
Description | Orange yellow crystalline powder; Novisible evidence of contamination by foreign matter | Yellow |
Identification A: | IR spectrum exhibits maxima only at the same wavelengths as that of a similar preparation of the USP reference standard | Conforms |
Identification B: | UV spectrum exhibits maxima and minima only at the same wavelengths as that of a similar preparation of the USP reference standard | Conforms |
Residue on ignition | Not more than 0.1% | 0.08% |
Specific Rotation | +19° to +24° | +20.6° |
Water content | Not more than 12.0% | 10.30% |
Assay(calculated on anhydrous basis) | 98.0% to 102.0% | 99.40% |
Chromatographic Purity | Total Not more than 2.0% | 0.70% |
Individual Not more than 0.5% | 0.20% |
Function&Application
Used as a antineoplastic and antirheumatic. A folic Acid antagonist.
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