1-1000 Grams
$50.00
≥1001 Grams
$20.00
Cephalosporins are a class of broad-spectrum semi-synthetic antibiotic, penicillin, compared with a wider antibacterial spectrum, penicillin-resistant enzymes, high efficacy, low toxicity and fewer allergic reactions, etc., in the anti-infective therapy occupies an important position.
Product performance: This product is white or white crystalline powder, odorless, bitter taste, easily soluble in water, aqueous solution more stable, can be stored at room temperature for 24 hours.
Other name: Cefotaxime sodium salt; Cefotaxime sodium; Claforan; sodium salt of 7-[2-(2-amino-4-thiazolyl)glyoxylamido]-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 7 (Z)-(O-methyloxime), acetate (ester); (6r-(6alpha,7beta(z)))-3-((acetyloxy)methyl)-(((2-amine-4-thiazolyl)(methoxyimino)acetyl)amino)-8-oxo-5-thia-1-azabicyclo(4,2,0)oct-2-ene-2-carboxylic acid monosodium salt; sodium (6R,7R)-3-[(acetyloxy)methyl]-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2E)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)-1-oxoethyl]amino]-8-oxo-, sodium salt, (6R,7R)- (1:1)
CAS NO.: 64485-93-4
EINECS NO.: 264-915-9
MF: C16H16N5NaO7S2
MW: 477.45
Appearance:White crystalline powder
Specification:99%min
Standard: EP/BP/USP
Odor: odorless
Items | Specification | Analysis Result | |
Appearance | White to light yellow crystalline powder | Conform | |
Identification | 1. The retention times of the major peaks in the chromatogram of the assay preparation correspond to those of the Standard preparation obtained in the assay | Conform | |
2. The IR absorption spectrum of the substance to be examined corresponds to that of the reference standard. | Conform | ||
Specific Rotation | -75°~-88° | -84° | |
Crystallinity | Meets the USP test requirements | Conform | |
PH | 2.6~4.1 | 3.6 | |
Water Content | 9.0%~12.0% | 10.4 | |
Residue of ignition | Not more than 0.1% | Conform | |
Heavy Metals | Not more than 20ppm | Conform | |
Chromatographic purity | Meets the USP test requirements | Conform | |
Assay (anhydrous) | 95.0%~103.0% | 99.8% | |
Related Impurities | Individual impurities | Not more than1.00% | 0.30% |
Total impurities | Not more than2.00% | 0.80% |
The main clinical infection for susceptible strains of meningitis, pneumonia, skin and soft tissue infections, peritonitis, urinary tract infections, gonorrhea, liver and gallbladder infection, surgical trauma, sepsis, and genital infections. As a treatment for gonorrhea has been first-line drugs
Cefotaxime Sodium is used for the Treatment of infections of lower respiratory tract including pneumonia, urinary tract, skin and skin structures, bone and joints; treatment of bacteremia/septicemia, CNS infections, intra-abdominal infections including peritonitis, gynecological infections including pelvic inflammatory disease, endometritis and pelvic cellulitis caused by susceptible strains of specific microorganisms; perioperative prophylaxis.
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