1-1000 Kilograms
$650.00
≥1001 Kilograms
$550.00
Product Description
Gentamicin Sulfate, a water-soluble antibiotic of the aminoglycoside group, is derived by the growth of Micromonospora purpurea, an actinomycete.
Gentamicin is an aminoglycoside antibiotic composed of a mixture of related gentamicin components and fractions and is used to treat many types of bacterial infections,
particularly those caused by Gram-negative organisms.
Gentamicin is also ototoxic and nephrotoxic, with this toxicity remaining a major problem in clinical use.
Certification of Analysis
ITEMS | SPECIFICATION | RESULTS | |
BP2010 /EP6 | Appearance | crystalline powder | Conforms |
Melting point | About 205°C | 206.4°C~206.7°C | |
Identification | Meet the requirements | Conforms | |
Appearance of solution | Clear, not more intense than Y7 | Conforms | |
PH | 2.4~3.0 | 2.60 | |
Loss on drying | ≤0.5% | 0.04% | |
Sulphated ash | ≤0.1% | 0.01% | |
Heavy metals | ≤20 ppm | <20 ppm | |
Related substances | ≤0.25% | Conforms | |
Assay | 99.0%~101.0% | 99.8% | |
USP32 | Identification | Meet the requirements | Conforms |
Loss on drying | ≤0.5% | 0.04% | |
Residue on ignition | ≤0.1% | 0.01% | |
Heavy metals | ≤0.003% | <0.003% | |
Residue solvent - Ethanol | ≤0.5% | <0.04% | |
Chloride | 16.9%~17.6% | 17.1% | |
Assay | 98.0%~102.0% | 100.0% | |
Conclusion: The product complies with BP2010/USP32/EP6 standard |
Function&Application
1. Colistin sulphate is the basic peptide antibiotics, mainly for the prevention and treatment of susceptible infections and promote animal growth.
2. Colistin sulphate can be combined with the cell membrane lipoprotein phosphate free, making the cell membrane surface tension decreases, increased permeability, resulting in the cytoplasm outflow of cell death.
3. Colistin sulphate has a strong inhibitory effect against gram-negative bacteria (particularly E. coli, Salmonella, Pseudomonas aeruginosa, Proteus and Haemophilus, etc.),has no effect on Gram-positive bacteria (Staphylococcus aureus and except hemolytic streptococcus outside) and fungi.
4. Colistin sulfate oral is difficult to absorb, less toxic, easy to cause drug residues, easy to produce drug resistance.
Qingdao Sigma chemical Co., Ltd is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
The aim of Qingdao Sigma chemical Co., Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
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