1-9 Kilograms
$176.00
≥10 Kilograms
$159.00
Product description
1.Buflomedil Hydrochloride
2.CAS No: 35543-24-9
3.MF No: C17H26C1NO4
4.Quality Standard :EP6.0/BP2010
5.Documents:DMF
TEST ITEM | STANDARDS REQUIRED |
[Characters] | A white or almost white, |
Appearance | freely soluble in water, |
Solubility | soluble in alcohol, |
Melting point | very slightlysoluble in acetone. |
[Identification] | at about 195 °C, with decomposition. |
A: absorption | shows an absorption maximum at 275 nm |
Buflomedil hydrochloride is a vasoactive drug with a variety of pharmacological effects, chemical name 2 ', 4', 6'-trimethoxy-4- (1-pyrrolidinyl) butyrylbenzene hydrochloride. The main pharmacological effect of buflomedil is to inhibit α-adrenergic receptors, inhibit platelet aggregation, enhance erythrocyte deformability, nonspecific calcium antagonism and enhance the use of oxygen, thereby improving ischemic tissue nutrient flow.
CERTIFICATE OF ANALYSIS | |||||||
Items | Standard | Results | |||||
Characters | White or almost white, microcrystalline powder. | Almost white, microcrystalline powder. | |||||
Melting point | About 195 °C, with decomposition. | 194.5~197.0°C | |||||
Identification | The solution shows an absorption maximum at 275 nm. The specific absorbance at the maximum is 143 to 149. | Qualified | |||||
IR | |||||||
TLC | |||||||
Gives reaction of chlorides | |||||||
Appearance of solution | Meets the requirements | Qualified | |||||
pH | 5.0~6.5 | 5.93 | |||||
Related substances | Individaul impurity≤0.25% | 0.01% | |||||
Total impurities≤0.5% | 0.02% | ||||||
Heavy metals | ≤0.001% | <0.001% | |||||
Loss on drying | ≤0.5% | 0.06% | |||||
Sulphated ash | ≤0.1% | 0.03% | |||||
Assay | 98.5%~101.5% | 99.15% | |||||
CONCLUSION: | The product complies to the standard of BP2010,EP6.0. |
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