1. The API

2. Retinoic acid analogues, adaline, is a RAR beta, and RAR gamma receptor agonist. Adapalin inhibits cell proliferation and induces apoptosis of colorectal cancer cells in vitro. Adapalin gel is an effective treatment for acne.

3.  Retinoic acid analogs. Adapalene is an agonist of RARβ, and RARγ receptor. Adapalene inhibits cell proliferation and inducing apoptosis in colorectal cancer cells in vitro. Adapalene gel is an effective medication for treatment of acne.

4.  Adapalene (cas.no:106685-40-9) is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne  and is also used (off-label) to treat keratosis pilaris as well as other skin conditions. It exerts excellent effect in acne condition  where the comedones are predominant.

Qingdao Sigma Chemical Co., Ltd.is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.

The aim of Qingdao Sigma Chemical Co., Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.