Top quality Irbesartan 138402-11-6 with best price on hot selling !
  • Item No.Irbesartan
    MOQ1 Kilogram / Kilograms
    description
    Product Description

    company

    Irbesartan is an angiotensin II receptor antagonist used mainly for the treatment of hypertension. As with all angiotensin II receptor antagonists, irbesartan is indicated for the treatment of hypertension. Irbesartan may also delay progression of diabetic nephropathy and is also indicated for the reduction of renal disease progression in patients with type 2 diabetes, hypertension and microalbuminuria (>30 mg/24 hours) or proteinuria (>900 mg/24 hours).

    Basic Information

    Basic Information.png 

    product NameIrbesartan
    SynonymsIrbesartan (GMP); 3-butyl-2-[[4-[2-(2h-tetrazol-5-yl)phenyl]phenyl]methyl]-2,4-diazaspiro[4.4]non-3-en-1-one; 2-BUTYL-3-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,3-DIAZASPIRO[4.4]NON-1-EN-4-ONE; BMS-186295; AVAPRO; APROVEL; SR-47436; 2-butyl-3-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one
    MolecularFormulaC25H28N6O
    MolecularWeight428.53
    CAS NO138402-11-6
    Density1.3g/cm 3
    Melting point180-181°C
    Boiling point648.6°C at 760 mmHg
    Refractive index1.689
    Flash point346°C
    VapourPressur 1.05E-16mmHg at 25°C
    Water NMT 0.5%
    Limit of azideNMT 10ppm
    Heavy metalsNMT 0.002%
    AppearanceWhite  to  Off-white,  crystalline powder

     

     

    Test  Item

    Analysis  Specification

    Result

    Description

     white to off-white crystalline powder

    white crystalline powder

    Identification IRspectrum

    Meets the requirements

    Meets the requirements

    UVspectrum

    Meets the requirements

    Meets the requirements

    Specific rotation

    +324.~+328.

    +327.7.

    Loss on drying(%)

    0.3max

    0.10

    Residue on ignition(%)

    0.2max

    0.01

    Heavy Metals(%)

    0.002max

    <0.002

    Limit of Lovastatin related compound A(%)

    0.5max

    0.22

    Individual impurity (%)

    0.2max

    0.13

    Total impurities (%)

    1.0max

    0.5

    Assay(%)

    98.5~101.0

    99.50

    Conclusion

    Conform to the requirements of USP30 Edition

    Functions

    .png As with all angiotensin II receptor antagonists, irbesartan is indicated for the treatment of hypertension. Irbesartan may also delay progression of diabetic nephropathy and is also indicated for the reduction of renal disease progression in patients with type 2 diabetes, hypertension and microalbuminuria (>30 mg/24 hours) or proteinuria.

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    Company Information

    Qingdao Sigma Chemical Co., Ltd.is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.

    The aim of Qingdao Sigma Chemical Co., Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
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