Factory provide high purity Hair Loss Products Setipiprant with full stock!

1-1000 Grams

$20.00

≥1001 Grams

$1.00

  • Item No.top
    MOQ1 Gram / Grams
    description
    Product Description
     

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    Specifciation:

                                 1.Competitive price
                                 2.Fast Delivery Within 2 days
                                 3.SGS , BV, GMP,ISO approve
                                 4.Professional factory

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    Description

    1.Name:Setipiprant
    2CAS No:866460-33-5
    3.Purity:99%min

    4.Appearance:white powder
    5.Assay:HPLC 99%
     

    Product Description:
    Setipiprant Powder (INN) (developmental code names ACT-129,968, KYTH-105) is a drug originally developed by Actelion which acts as a selective, orally available antagonist of the prostaglandin D2 receptor 2 (DP2). It was initially researched as a treatment for allergies and inflammatory disorders, particularly asthma, but despite being well tolerated in clinical trials and showing reasonable efficacy against allergen-induced airway responses in asthmatic patients, it failed to show sufficient advantages over existing drugs and was discontinued from further development in this application. However, following the discovery in 2012 that the prostaglandin D2 receptor (DP/PGD2) is expressed at high levels in the scalp of men affected by male pattern baldness, the rights to setipiprant were acquired by Kythera with a view to potentially developing this drug as a novel treatment for baldness, with a previously unexploited mechanism of action. While it is too early to tell whether setipiprant will be an effective treatment for this condition, the favorable pharmacokinetics and relative lack of side
    effects seen in earlier clinical trials mean that fresh clinical trials for this new application can be conducted fairly quickly.A phase 2A study is underway to evaluate the safety, tolerability, and efficacy of oral setipiprant relative to a placebo and the active comparator, finasteride, in 18 to 41 years old males with androgenetic alopecia.
    Functions

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     1. For maximum effect, the solution should be in contact with the scalp for hours before being washed out. It does not seem capable of reducing DHT or the enzyme responsible for its accumulation around the hair follicle, 5-aliha reductase.
    2. which are the main causes of male pattern baldness in genetically susceptible individuals. Therefore, when treatment is stopped, the DHT already accumlated around the follicle has its expected effect, and the follicle usually shrinks again and eventually dies.
    3. Setipiprant powder can promote hair regrowth,slow or stop hair loss and treat high blood pressure.Setipiprant needs to be applied once or twice daily for hair to be maintained

    Analysis

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    Item
    Specifications
    Results
    Assay (HPLC)
    ≥98.0%
    99.50%
    Appearance
    White powder
    Conforms
    IHNMR
    complies with the structure
    complies
    LC-MS
    complies with MW
    complies
    Loss on drying  
    max.0.5%   
    0.05%
    Residue on ignition                    
    max.0.1%  
    0.05%
    Heavy metals                      
    max.30ppm    
    complies
    Related substance  (TLC)  
    max. 1.0%
    complies
    Total impurities                       
    max. 2.0%
    complies
    Packaging & Shipping

     

     

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    Our Services

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    Company Information

     

    Qingdao xigema Chemical Co.,Ltd is a global chemical industry manufacturers and suppliers of pharmaceuticals 

    and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.

    The aim of xigema is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.

    xigema has become the "Top 500 Chinese manufacturing companies","Top 20 of global chemical sales".xigema has 21 subsidiaries and holding companies.

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    FAQ

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    Q1: Are you a manufacturer?
    Answer: Yes, we are factory founded on 2002.

    Q2: How to contact with us?
    Click the Alibaba "Contact Supplier" And then send us message the product you interest in, you will get reply within 24 hours.

    Q3:Which kind of payment terms do you accept?
    For small order,you can pay by T/T,Western Union or Paypal,nomal order by T/T to our company account

    Q4:Can you give me a discount price?
    Surely,It depend on your qty

    Q5:How can i get a sample?
    free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.

    Q6: How to confirm the Product Quality before placing orders?
    A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

    Q7:How do you treat quality complaint?
    A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

    If you are interested,welcome to contact with us.
    Pls send message if you are interested,click "send" as below ^.^

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    https://www.sigmachemical.com.cn/

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