Top quality CAS 7481-89-2 Zalcitabine with reasonable price and fast delivery on hot selling
  • Item No.99%
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    Top quality CAS 7481-89-2 Zalcitabine

     

     

    Product Description

     

     

     

     

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    Name:zalcitabine

    Synonyms:2',3'-Dideoxycytidine;Dideoxycytidine;Hivid;NSC 606170;Ro 24-2027/000;ddC

    Specification: 99%

    CAS NO.: 7481-89-2

    Appearance:white to off-white cyrstalline powder

    Molecular formula:C9H13N3O3

    Molecular weight:211.2178 

    Melting point:210-214°C 

     

     

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    Items

    Specification

    Appearance:

    A white to almost white crystalline powder

    Identification:

    According to USP27

    Water:

    Not more than 0.3%

    Specific rotation:

    +73 to +77

    Heavy metals:

    Not more than 20ppm

    Residue on ignition:

    Not more than 0.1%

    Individual impurities:

    Not more than 0.3%

    Total impurities:

    Not more than 2.0%

    pH value(2.5% solution):

    7-8

     

     

     

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    Zalcitabine (2′-3′-dideoxycytidine, ddC), also called dideoxycytidine, is a nucleoside analog reverse transcriptase inhibitor (NRTI) sold under the trade name Hivid. Zalcitabine was the third antiretroviral to be approved for the treatment of HIV/AIDS. It is used as part of acombination regimen.

     

    Zalcitabine appears less potent than some other nucleoside RTIs, has an inconvenient three-times daily frequency and is associated with serious adverse events. For these reasons it is now rarely used to treat human immunodeficiency virus (HIV), and it has even been removed from pharmacies entirely insomecountries.

    Zalcitabine is an analog of pyrimidine. It is a derivative of the naturally existing deoxycytidine, made by replacing the hydroxyl group in position 3' with a hydrogen.

     

    It is phosphorylated in T cells and other HIV target cells into its active triphosphate form, ddCTP. This active metabolite works as a substrate for HIV reverse transcriptase, and also by incorporation into the viral DNA, hence terminating the chain elongation due to the missing hydroxyl group. Since zalcitabine is areverse transcriptase inhibitor it possesses activity only againstretroviruses.

     

    Packaging & Shipping

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    Our Services

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    Company Information
    Qingdao Xigema Chemical Co., Ltd is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.

    The aim of Xigema is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.

    Xigema has become the "Top 500 Chinese manufacturing companies","Top 20 of global chemical sales".Xigema has 21 subsidiaries and holding companies.
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    FAQ
    Q1: Are you a manufacturer?
    Answer: Yes, we are factory founded on 2002.
     
    Q2: How to contact with us?
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    Q3:Which kind of payment terms do you accept?
    For small order,you can pay by T/T,Western Union or Paypal,nomal order by T/T to our company account
     
    Q4:Can you give me a discount price?
    Surely,It depend on your qty
     
    Q5:How can i get a sample?
    free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
     
    Q6: How to confirm the Product Quality before placing orders?
    A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
     
    Q7:How do you treat quality complaint?
    A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
     
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