Gossypol-acetic acid/ Acetate gossypol /Gossypol acetate 98%

Specification: 98%
Test Method: HPLC
CAS: 12542-36-8
Certification:ISO, GMP, KOSHER
Extract Part: seed
Extraction Type: Solvent Extraction 
Appearance: Light yellow crystalline powder

Product introduction: 

Gossypol has a yellow pigment and is found in cotton plants. It occurs mainly in the root and/or seeds of different species of cotton plants. Gossypol can have various chemical structures. It can exist in three forms: gossypol, gossypol acetic acid, and gossypol formic acid. All of these forms have very similar biological properties. Gossypol is a type of aldehyde, meaning that it has a formyl group. The formation of gossypol occurs through an isoprenoid pathway. Isoprenoid pathways are common among secondary metabolites. Gossypol's main function in the cotton plant is to act as an enzyme inhibitor. An example of gossypol's enzyme inhibition is its ability to inhibit nicotinamide adenine dinucleotide-linked enzymes of Trypanosoma cruzi. Trypanosoma cruzi is a parasite which causes Chaga's disease.

For some time it was believed that gossypol was merely a waste product produced during the processing of cottonseed products. Extensive studies have shown that gossypol has other functions. Many of the more popular studies on gossypol discuss how it can act as a male contraceptive. Gossypol has also been linked to causing hypokalemic paralysis. Hypokalemic paralysis is a disease characterized by muscle weakness or paralysis with a matching fall in potassium levels in the blood. Hypokalemic paralysis associated with gossypol in-take usually occurs in March, when vegetables are in short supply, and in September, when people are sweating a lot. This side effect of gossypol in-take is very rare however. Gossypol induced hypokalemic paralysis is easily treatable with potassium repletion.

Main Functions:  

It is the natural male contraceptive and is also used for treatment of female gynecological disorders. Clinic studies indicate that it has potent antitumor and antivirus acitivity and has used for treating the cancer of adrenal cortex and bladder cancer.

Application:

As pharmaceutical & cosmetic raw materials

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