High Purity 99% Afatinib with reasonable price CAS 439081-18-2
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    MOQ1 Gram / Grams
    description
    Product Description

                

    company 

    Afatinib is a potent and irreversible dual inhibitor of EGFR and human epidermal growth factor receptor 2 (HER2) tyrosine kinase.White solid.

    Functions

     

    Afatinib is a drug approved for the treatment non-small cell lung carcinoma(NSCLC), developed by Boehringer Ingelheim.

     

    It acts as a angiokinase inhibitor.

     

    Like lapatinib and neratinib, afatinib is a tyrosine kinase inhibitor (TKI) that also irreversibly inhibits human epidermal

    growth factor receptor 2 (Her2) and epidermal growth factor receptor (EGFR) kinases. Afatinib is not only active against

    EGFR mutations targeted by first generation TKIs likeerlotinib or gefitinib, but also against those not sensitive to these

     

    standard therapies. Because of its additional activity against Her2, it is being investigated for breast cancer as well as

    other EGFR and Her2 driven cancers.

    Analysis

     

    Product Name
    Afatinib 
    CAS No
    439081-18-2
    Formula
    C24H25ClFN5O3
    Molecular Weight
    485.93800
    Synonyms
    (S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide;
    Tovok;
    BIBW2992
    Exact Mass
    485.16300
    LogP
    4.53590
    Color
    White powder

     

    Packaging & Shipping

     

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    Our Services

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    FAQ

    Q1: Are you a manufacturer?
    Answer: Yes, we are factory founded on 2002.
     
    Q2: How to contact with us?
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    Q3:Which kind of payment terms do you accept?
    For small order,you can pay by T/T,Western Union or Paypal,nomal order by T/T to our company account
     
    Q4:Can you give me a discount price?
    Surely,It depend on your qty
     
    Q5:How can i get a sample?
    free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
     
    Q6: How to confirm the Product Quality before placing orders?
    A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
     
    Q7:How do you treat quality complaint?
    A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.


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